Abstract
To evaluate the severity of hypertrophic cardiomyopathy (HCM) according to global, regional, and multi-layer longitudinal strain (LS) analysis using speckle-tracking echocardiography. From February 2007 to November 2014, we prospectively evaluated 375 consecutive HCM patients referred to our specialized cardiomyopathy center. Demographics, clinical, and rest and exercise echocardiographic parameters were collected according to a completely standardized protocol. Global, regional, and multilayer strain analyses were performed. Correlations between LS and other characteristics were evaluated, and we assessed their prognostic value to predict sudden cardiac death (SCD) or appropriate implantable cardioverter defibrillator (ICD) shocks during follow-up, using Cox proportional hazards analyses. We finally included 217 patients (50.1 ± 15.6 years, 67% male) but only 179 (82%) had LS analysis of sufficient quality. An inverse relation was observed between the mean basal left ventricular (LV) LS and diastolic parameters [E/Ea (r = - 0.30) and left atrium indexed volume (r = - 0.23)], as well as between the resting LV outflow-tract maximal gradient (r = - 0.26) or during peak exercise (r = - 0.20). Mean LS in the LV hypertrophic area wa...Continue Reading
References
Jan 24, 2003·The New England Journal of Medicine·Martin S MaronBarry J Maron
Sep 29, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Marina LeitmanZvi Vered
Mar 21, 2006·Journal of the American College of Cardiology·Karim SerriStephane Lafitte
Jun 27, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Rosa SicariUNKNOWN European Association of Echocardiography
Apr 7, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Giovanni Di SalvoRaffaele Calabrò
May 26, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Martin S Maron, Natesa G Pandian
Jul 14, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Lawrence G RudskiNelson B Schiller
Nov 10, 2011·Circulation·Bernard J GershUNKNOWN Society of Thoracic Surgeons
Jan 25, 2012·European Heart Journal Cardiovascular Imaging·Makoto SaitoJitsuo Higaki
Apr 16, 2013·JACC. Cardiovascular Imaging·Sebastian I SarvariThor Edvardsen
Feb 7, 2014·The International Journal of Cardiovascular Imaging·Philippe DebonnaireNina Ajmone Marsan
Jun 18, 2014·European Heart Journal·Perry Elliott
Jul 7, 2014·Journal of the American College of Cardiology·Barry J MaronMartin S Maron
Aug 6, 2014·Circulation·Raymond H ChanMartin S Maron
Dec 3, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Patricia ReantStephane Lafitte
Feb 26, 2015·European Heart Journal Cardiovascular Imaging·Roberto M LangJens-Uwe Voigt
Feb 28, 2015·International Journal of Cardiology·Koya OzawaYoshio Kobayashi
Feb 10, 2016·Heart·Patricia ReantWilliam J McKenna
Feb 14, 2016·European Heart Journal Cardiovascular Imaging·Trine F HalandKristina H Haugaa
Jun 10, 2016·Echocardiography·Vincenzo Schiano-LomorielloFabrizio Pane
Oct 19, 2016·The International Journal of Cardiovascular Imaging·Jérôme PeyrouStéphane Lafitte
Nov 24, 2016·The International Journal of Cardiovascular Imaging·Lu ZhangGuang Zhi
Nov 26, 2016·International Journal of Cardiology·Koya OzawaYoshio Kobayashi
Apr 27, 2017·Echocardiography·Ozkan CandanCem Doğan
Jul 7, 2017·Circulation. Cardiovascular Imaging·Yasmine L HiemstraNina Ajmone Marsan
Oct 19, 2017·Cardiology in Review·Thomas ZegkosHaralambos Karvounis
Citations
Dec 4, 2019·Heart Failure Reviews·Fancesco BanderaMatteo Cameli
Jun 27, 2020·European Radiology·Liping YangKezheng Wang
Mar 29, 2020·Heart Failure Reviews·Maria Concetta PastoreMatteo Cameli
Feb 9, 2021·The International Journal of Cardiovascular Imaging·Zsofia DohyHajnalka Vago
Jan 27, 2020·Heart, Lung & Circulation·John YoungerJohn J Atherton
May 16, 2021·Heart Failure Reviews·Efstathios D PagoureliasVassilios P Vassilikos
Jun 26, 2021·The American Journal of Cardiology·Ethan J RowinMartin S Maron
Aug 8, 2021·Diagnostics·Elżbieta WabichLudmiła Daniłowicz-Szymanowicz
Aug 16, 2021·Journal of Electrocardiology·Erick JimenezDaniel Cortez
Sep 4, 2021·Indian Heart Journal·K RakeshHaridasn Vellani