Characterization of Idiopathic Choroidal Neovascularization Using Fluorescein Angiography, Indocyanine Green Angiography, and Optical Coherence Tomography Angiography

Ophthalmic Surgery, Lasers & Imaging Retina
Atul KumarAnu Sharma

Abstract

To assess the usefulness of optical coherence tomography angiography (OCTA) in cases of idiopathic choroidal neovascularization (iCNV). Seven eyes with suspected iCNV were evaluated using OCT, OCTA, fluorescein angiography (FA), and indocyanine green angiography (ICGA) and were followed up between 3 weeks and 4 weeks following an intravitreal anti-vascular endothelial growth factor (VEGF) injection. The utility of OCTA in the diagnosis and characterization of morphology of iCNV at baseline and follow-up was assessed. Morphology of vasculature comprising iCNV could be detected in all cases (100%) on OCTA and in 57% cases on ICGA. FA only detected hyperfluorescence and not individual vessel morphology. After anti-VEGF injection, the mean logMAR visual acuity improved from 0.55 to 0.27. A qualitative scale to assess response of therapy is suggested. OCTA is a useful, noninvasive tool to detect, characterize, and follow-up on cases of suspected iCNV with utility comparable to or even better than traditional angiography techniques. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:516-522.].

References

Oct 24, 2007·Indian Journal of Ophthalmology·Mahesh P ShanmugamNitin S Shetty
Jul 15, 2015·American Journal of Ophthalmology·Laura KuehleweinDavid Sarraf
Mar 15, 2016·American Journal of Ophthalmology·Manabu MiyataNagahisa Yoshimura
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Methods Mentioned

BETA
imaging technique

Software Mentioned

Heidelberg Eye Explorer
ImageJ
OCTA

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