Characterization of in vivo wear debris from ceramic-ceramic total hip arthroplasties

Journal of Biomedical Materials Research
S LerougeL Sedel

Abstract

In contrast to the much-studied mechanism of aseptic loosening of the metal-polyethylene joint couple, the mechanism responsible for failure of ceramic-ceramic (CC) total hip arthroplasties (THAs) has not been evaluated. The aim of this study was to conduct a systematic characterization of the in vivo wear debris from 15 cases of CC THAs revised for aseptic loosening. Two methods were used to evaluate the wear debris; a semiquantitative histological analysis of H&E-stained periprosthetic pseudomembranes; and an evaluation of isolated debris particles using SEM, energy-dispersive X-ray analysis, and image analysis. The three main types of particulate debris identified were titanium alloy (TiAlV) and alumina ceramic (Al2O3) of prosthetic origin, and zirconium dioxide (ZrO2) from the contrast agent used in the cement for prosthetic fixation. Alumina debris was present in the smallest proportion (12%) and was consistent with the low wear rate of the CC joint couple. Zirconium dioxide debris was present in the greatest proportion (76%) and was an unexpected finding. The ZrO2 debris represented microstructural grains of the original ZrO2 particles added as contrast agent to the cement. The presence of a histiocytic foreign body react...Continue Reading

References

May 1, 1992·The Journal of Bone and Joint Surgery. British Volume·L Sedel
May 1, 1992·The Journal of Bone and Joint Surgery. British Volume·J M LeeP G Bullough
Jan 1, 1991·Archives of Orthopaedic and Trauma Surgery·R MichelF Löer
Dec 1, 1989·Journal of Biomedical Materials Research·J M DorlotA Meunier
Dec 1, 1988·Journal of Biomedical Materials Research·P BoutinJ Witvoet
Apr 1, 1987·Journal of Biomedical Materials Research·A PizzoferratoC Tarabusi
Sep 1, 1995·The Journal of Bone and Joint Surgery. American Volume·W J MaloneyH Rubash
Jan 1, 1995·Journal of Biomedical Materials Research·P CampbellH C Amstutz
Jan 1, 1994·Journal of Applied Biomaterials : an Official Journal of the Society for Biomaterials·T P SchmalzriedW H Harris

❮ Previous
Next ❯

Citations

May 13, 1999·Journal of Biomedical Materials Research·T KuboY Hirasawa
Aug 22, 2000·Journal of Biomedical Materials Research·M HamadoucheL Sedel
Aug 16, 2001·Journal of Biomedical Materials Research·E A MagnissalisC Zacharis
Jan 5, 2002·Journal of Biomedical Materials Research·Toshihiro AkisueYuichi Mochida
Oct 2, 2004·Analytical and Bioanalytical Chemistry·Giuseppe Pezzotti
Feb 21, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Alain PetitOlga L Huk
May 21, 2008·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·B Sonny BalMohamed N Rahaman
Aug 7, 2009·Der Orthopäde·C KaddickM A Wimmer
Jan 20, 2017·Biomedical Materials·Pierre-Antoine FayeAlexis Desmoulière
Oct 20, 2000·Clinical Orthopaedics and Related Research·P BizotR Nizard
Feb 24, 2001·Journal of Biomedical Materials Research·S K Yen, S W Hsu
Aug 15, 2001·Clinical Orthopaedics and Related Research·Y MochidaT W Bauer
Sep 25, 1999·Journal of Biomedical Materials Research·Y JossetD Laurent-Maquin
Jan 5, 2002·Clinical Orthopaedics and Related Research·P BizotL Sedel
Oct 20, 2000·Clinical Orthopaedics and Related Research·M J ArchibeckJ Black
Nov 4, 1998·The Journal of Bone and Joint Surgery. American Volume·T R YoonW J Maloney
Feb 24, 2007·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·L Sedel, A Raould
May 25, 2005·The Journal of Bone and Joint Surgery. British Volume·R NizardP Bizot
Jun 27, 2012·The Journal of Bone and Joint Surgery. British Volume·C I EspositoW K Walter
Jul 29, 2010·Clinical Orthopaedics and Related Research·Bernd FinkMichael Hahn
Apr 5, 2005·Clinical Orthopaedics and Related Research·S P ZyskA Veihelmann
Jan 22, 2005·Clinical Orthopaedics and Related Research·Didier HannoucheLaurent Sedel
Oct 30, 2020·Journal of Microscopy·D ChappardL Hubert
Oct 8, 2020·Orthopaedics & Traumatology, Surgery & Research : OTSR·Louis RonyDaniel Chappard
Nov 10, 2020·Frontiers in Bioengineering and Biotechnology·Michel AssadSimon Authier
Dec 26, 2001·Chemical Reviews·S B Yu, A D Watson
Jul 19, 2005·Biomaterials·John L Brash

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.