PMID: 20622465Jul 14, 2010Paper

Characterization of juvenile hormone epoxide hydrolase and related genes in the larval development of the silkworm Bombyx mori

Bioscience, Biotechnology, and Biochemistry
Atsushi SeinoT Shiotsuki

Abstract

Juvenile hormone epoxide hydrolases (JHEHs) are a family of enzymes that hydrolyze juvenile hormones (JHs). They are important in terms of organ-specific regulation and irreversible degradation. In contrast to three JHEH genes (jheh) in Drosophila melanogaster and five jheh in Tribolium castaneum, only one jheh gene has been reported to date in lepidopteran insects. By searching a genome database of the silkworm, KAIKOBLAST, five JHEH-related genes (jheh-r), in addition to Bmjheh, were found. Developmental changes in mRNA expression were brought about revealing several unique patterns for each of jheh-r as to developmental stages and organ-specificity. Recombinant proteins of JHEH-r were expressed using a baculovirus system to evaluate their enzymatic activities. Three of the five JHEH-r recombinant proteins had JH hydrolytic activities. This is the first report on lepidopteran jheh-related genes and also provides the comprehensive analysis of multiple jheh-related genes in an insect species with respect to their functions in enzyme activities.

References

Aug 6, 1998·Insect Biochemistry and Molecular Biology·S DebernardB D Hammock
Oct 16, 1999·Nature·J W Truman, L M Riddiford
Jul 19, 2002·Archives of Insect Biochemistry and Physiology·Katherine C L KeiserNancy Wisnewski
Nov 14, 2002·Insect Biochemistry and Molecular Biology·Tonya F SeversonBruce D Hammock
Oct 8, 2003·Proceedings of the National Academy of Sciences of the United States of America·Tetsuro Shinoda, Kyo Itoyama
May 15, 2004·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Kazuei MitaTakuji Sasaki
Dec 14, 2004·Science·Qingyou XiaUNKNOWN Biology Analysis Group
Feb 1, 2005·Insect Biochemistry and Molecular Biology·Qi-Rui ZhangSheng Li
Mar 8, 2005·Progress in Lipid Research·John W NewmanBruce D Hammock
Aug 10, 2005·Proceedings of the National Academy of Sciences of the United States of America·Anjang TanTakahiro Shiotsuki
Jan 6, 2009·Insect Biochemistry and Molecular Biology·UNKNOWN International Silkworm Genome Consortium
Jan 12, 2010·Insect Biochemistry and Molecular Biology·Takuya TsubotaTakahiro Shiotsuki

❮ Previous
Next ❯

Citations

Apr 30, 2013·BMC Genomics·Jean-Michel CarterCasper J Breuker
Nov 13, 2010·Bioscience, Biotechnology, and Biochemistry·Takuya TsubotaTakahiro Shiotsuki
Jan 2, 2013·Insect Biochemistry and Molecular Biology·Shizuo G KamitaBruce D Hammock
May 25, 2013·Archives of Insect Biochemistry and Physiology·Shizuo G KamitaBryce W Falk
Jun 7, 2014·Wiley Interdisciplinary Reviews. Developmental Biology·H Frederik NijhoutViviane Callier
Feb 18, 2015·Insect Biochemistry and Molecular Biology·Jiawen XuBruce D Hammock
Sep 1, 2014·Insect Biochemistry and Molecular Biology·Jiawen XuBruce D Hammock
Apr 13, 2017·Scientific Reports·Abudourusuli TusunGuirong Wang
Jan 7, 2017·Insect Biochemistry and Molecular Biology·Zhongjie ZhangAnjiang Tan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.