Characterization of macrolide resistance in Mycoplasma pneumoniae isolated from children in Shanghai, China

Diagnostic Microbiology and Infectious Disease
Yang LiuMinggui Wang

Abstract

One hundred Mycoplasma pneumoniae strains were isolated from pediatric patients from March 2008 to July 2009. Of 100 isolates, 90 (90%) were resistant to erythromycin (MICs >128 microg/mL for 88 strains and 64 microg/mL for 2 strains), azithromycin, and clarithromycin. Fluoroquinolones and tetracyclines maintain good activities against clinical M. pneumoniae isolates. Of 90 macrolide-resistant M. pneumoniae strains, 88 (98%) harbored an A-to-G transition mutation at position 2063 in 23S rRNA genes, and the remaining 2 showed either A2064G or A2063T mutation; the latter point mutation is newly discovered and reported. Ninety-three (93%) clinical isolates were classified into the P1 gene restriction fragment length polymorphism (RFLP) type I, and 7 (7%) were type II.

References

Oct 19, 2004·Clinical Microbiology Reviews·Ken B Waites, Deborah F Talkington
Nov 25, 2004·Antimicrobial Agents and Chemotherapy·Mayumi MatsuokaTsuguo Sasaki
May 27, 2005·Antimicrobial Agents and Chemotherapy·Miyuki MorozumiKimiko Ubukata
Sep 27, 2005·Current Drug Targets. Infectious Disorders·C M Bébéar, S Pereyre
Jan 27, 2006·Antimicrobial Agents and Chemotherapy·Satowa SuzukiTsuguo Sasaki
Oct 24, 2007·Antimicrobial Agents and Chemotherapy·Miyuki MorozumiUNKNOWN Acute Respiratory Diseases Study Group
Jul 23, 2008·Antimicrobial Agents and Chemotherapy·Bernard J WolffJonas M Winchell
Dec 17, 2008·Future Microbiology·Ken B WaitesT Prescott Atkinson
Mar 11, 2009·Antimicrobial Agents and Chemotherapy·Deli XinDawei Shi

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Citations

Sep 14, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Takafumi OkadaKimiko Ubukata
Mar 12, 2011·The Journal of Antimicrobial Chemotherapy·M ChironnaF Cardinale
Nov 16, 2012·The Journal of Antimicrobial Chemotherapy·Tsutomu ItagakiYoko Matsuzaki
Nov 22, 2012·The Journal of Antimicrobial Chemotherapy·Nicola Principi, Susanna Esposito
Jan 3, 2012·The Pediatric Infectious Disease Journal·Masaki YamadaGregory A Storch
Apr 3, 2012·The Pediatric Infectious Disease Journal·Susanna EspositoUrs B Schaad
Nov 2, 2012·The Pediatric Infectious Disease Journal·Yu SuzukiYoko Matsuzaki
Apr 30, 2011·Future Microbiology·Cécile BébéarOlivia Peuchant
Nov 5, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Rok KogojDarja Kese
Nov 26, 2013·Diagnostic Microbiology and Infectious Disease·Jinhong XiaoCuiming Zhu
Mar 13, 2014·Pediatrics International : Official Journal of the Japan Pediatric Society·Fujio KakuyaHiroki Kano
Jan 3, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S PereyreC Bébéar
Jul 26, 2016·Frontiers in Microbiology·Sabine PereyreCécile Bébéar
Dec 23, 2016·Japanese Journal of Infectious Diseases·Jia-Lu YuGen Lu
Mar 1, 2012·Korean journal of pediatrics·You-Sook Youn, Kyung-Yil Lee
Dec 29, 2013·Journal of Clinical Microbiology·Jessica L WallerJonas M Winchell
Dec 3, 2014·Antimicrobial Agents and Chemotherapy·Zibo ZhouFeng Tan
Nov 28, 2013·Antimicrobial Agents and Chemotherapy·Yunlian ZhouZhimin Chen
May 26, 2017·Clinical Microbiology Reviews·Ken B WaitesT Prescott Atkinson
Jan 10, 2013·Annals of Laboratory Medicine·Joo Hee HongKap Jun Yoon
Apr 26, 2012·The Journal of Antimicrobial Chemotherapy·Masatoshi NakataniNobuhiko Nomura
Jul 13, 2020·The Journal of Antimicrobial Chemotherapy·Belén RivayaLurdes Matas
Feb 21, 2018·Emerging Infectious Diseases·Maimuna CarrimAnne von Gottberg
Apr 16, 2011·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Harald MoiAnne Olaug Olsen
Jan 31, 2019·Antimicrobial Resistance and Infection Control·Fei ZhaoJianzhong Zhang
Aug 1, 2019·Epidemiology and Infection·Li-Wei GaoKun-Ling Shen
Nov 17, 2020·Frontiers in Cellular and Infection Microbiology·Fei ZhaoJianzhong Zhang
Apr 18, 2020·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Yi-Chen LeeHong-Ren Yu

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