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Characterization of molecular signatures of supratentorial ependymomas

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc

Aug 2, 2019

Matthew TorreDavid M Meredith

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Abstract

Ependymomas show poor correlation between World Health Organization grade and clinical outcome. A subgroup of supratentorial ependymomas are characterized by C11orf95-RELA fusions, presumed to be secondary to chromothripsis of chromosome 11, resulting in constitutive activation of the N...read more

Mentioned in this Paper

Biological Markers
Cell Adhesion Molecules
Chromosomes
Ependymoma
Immunohistochemistry
Neoplasms
Signal Pathways
World Health Organization
NF-kappa B
Cyclin D1
5
4
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Characterization of molecular signatures of supratentorial ependymomas

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc

Aug 2, 2019

Matthew TorreDavid M Meredith

PMID: 31375768

DOI: 10.1038/s41379-019-0329-2

Abstract

Ependymomas show poor correlation between World Health Organization grade and clinical outcome. A subgroup of supratentorial ependymomas are characterized by C11orf95-RELA fusions, presumed to be secondary to chromothripsis of chromosome 11, resulting in constitutive activation of the N...read more

Mentioned in this Paper

Biological Markers
Cell Adhesion Molecules
Chromosomes
Ependymoma
Immunohistochemistry
5
4

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