PMID: 3770773Jan 1, 1986Paper

Characterization of monoclonal antibodies directed against HLA class II molecules

Hybridoma
T CabreraF Garrido

Abstract

Four MAbs recognizing HLA class II antigens were produced by immunization with human leukemic cells, and were characterized through immunoprecipitation and cell distribution studies. They were tested against a panel of normal and leukemic cells, Epstein-Barr virus (EBV)-transformed homozygous typing cells (HTC)s, deletion mutant cell lines, and 11 other cell lines. The immunochemical studies revealed the presence of two bands of 34 and 28 kD, corresponding to the alpha- and beta-subunits of HLA class II antigens, respectively. The cell distribution studies led to the conclusion that GRB1, GRB2, and GRB3 MAbs recognize the HLA-DR monomorphic antigens, and that the GRB4 MAb seems to recognize basically the DR molecules but shows also a cross-reaction to DP molecules.

References

May 1, 1981·Molecular Immunology·S CarrelR S Accolla
Jan 1, 1982·Immunological Reviews·D A ShackelfordJ L Strominger
Jul 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·R S AccollaG Corte

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Citations

Mar 1, 1989·Clinical & Experimental Metastasis·F Ruiz-CabelloC Rivas
Jul 1, 1990·Clinical & Experimental Metastasis·F EstebanF Garrido
Oct 24, 2000·International Journal of Clinical & Laboratory Research·M A FernándezF Garrido
Aug 1, 1991·Immunobiology·J E FernándezF Garrido
Apr 25, 2000·Human Immunology·T CabreraF Garrido
Feb 15, 1990·International Journal of Cancer. Journal International Du Cancer·S PedrinaciF Garrido
Jan 1, 1991·International Journal of Cancer. Supplement = Journal International Du Cancer. Supplement·A ConchaF Garrido
Sep 1, 1992·Immunobiology·T CabreraF Garrido
Sep 1, 1991·Immunobiology·A ColladoF Garrido
Aug 1, 1989·Journal of Immunogenetics·A FerronF Garrido
Mar 15, 1989·International Journal of Cancer. Journal International Du Cancer·F EstebanF Garrido
Aug 1, 1995·European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics·A ConchaF Garrido
Aug 17, 1999·International Journal of Cancer. Journal International Du Cancer·P JiménezF Garrido

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