PMID: 109484Jun 1, 1979

Characterization of mouse allergens

The Journal of Allergy and Clinical Immunology
R P Siraganian, A L Sandberg


The major allergens present in mouse skin, serum, and urine have been identified. Skin extracts, serum, and urine were chromatographed, and the activities of the fractions were monitored by histamine release from the leukocytes of individuals sensitive to mice. Fractionation of skin extracts revealed two major allergens. The large allergen has a molecular weight of approximately 67,000 daltons and by biochemical and immunochemical criteria appears to be identical to mouse albumin. The smaller molecular weight allergen is approximately 17,000 daltons. The same two allergens are also found in mouse serum and mouse urine. Histamine release by leukocytes of individuals allergic to mice demonstrated that some individuals react predominantly to the large allergen, some to the small allergen, and one group of patients reacts to both allergens.


Aug 8, 2002·Current Allergy and Asthma Reports·Wanda Phipatanakul
Sep 1, 1980·Molecular Immunology·M J Schumacher
Jan 1, 1981·Molecular Immunology·U WahnR P Siraganian
Nov 4, 2000·Biochimica Et Biophysica Acta·R MäntyjärviT Virtanen
Jun 26, 2001·Allergy·S GordonA J Newman Taylor
Dec 21, 2000·ILAR Journal·R A Wood
Dec 11, 2002·ILAR Journal·R K Bush, Gregg M Stave
Jan 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J A Price, J L Longbottom
Jan 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C Schou
Jan 1, 1988·Clinical Allergy·J A Price, J L Longbottom
Jul 29, 1998·The Journal of Allergy and Clinical Immunology·R K BushP A Eggleston
Sep 18, 2013·Methods : a Companion to Methods in Enzymology·Ola B NilssonHans Grönlund
Mar 1, 2018·Frontiers in Immunology·Véronique SchultenAlessandro Sette

Related Concepts

Molecular Sieve Chromatography
Physical Dialysis
Immunodiffusion Measurement

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

The Tendon Seed Network

Tendons are rich in the extracellular matrix and are abundant throughout the body providing essential roles including structure and mobility. The transcriptome of tendons is being compiled to understand the micro-anatomical functioning of tendons. Discover the latest research pertaining to the Tendon Seed Network here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Incretins are metabolic hormones that stimulate a decrease in glucose levels in the blood and they have been implicated in glycemic regulation in the remission phase of type 1 diabetes. Here is the latest research.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Long COVID-19

“Long Covid-19” describes illness in patients who are reporting long-lasting effects of the SARS-CoV-19 infection, often long after they have recovered from acute Covid-19. Ongoing health issues often reported include low exercise tolerance and breathing difficulties, chronic tiredness, and mental health problems such as post-traumatic stress disorder and depression. This feed follows the latest research into Long Covid.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Related Papers

International Archives of Allergy and Applied Immunology
D Levy
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
C Schou
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
J A Price, J L Longbottom
© 2021 Meta ULC. All rights reserved