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Characterization of mucin-type oligosaccharides with the sialyl-Le(a) structure from human colorectal adenocarcinoma cells

Biochemical and Biophysical Research Communications

Aug 15, 1991

H KitagawaI Yamashina

Abstract

Oligosaccharides with the sialyl-Le(a) structure have been isolated on an affinity column of a monoclonal antibody, MSW 113, from mucin-type glycoproteins derived from the surfaces of SW 1116 and LS 180 cells, and their secretions. The oligosaccharides were polydisperse with respect to ...read more

Mentioned in this Paper

poly-N-acetyllactosamine
Monoclonal Antibodies
GLB1
Keratan-sulfate endo-1,4-b-galactosidase
Mucin-1 protein
Glycoproteins
Malignant Tumor of Colon
Citrobacter freundii
Adenocarcinoma of Large Intestine
Blood-group-substance endo-1,4-b-galactosidase
Paper Details
References
  • References2
  • Citations3
1

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Approximately 95% of all colon cancers are colon adenocarcinomas, which are associated with a significant reduction in or loss of goblet cells. Here is the latest research on colon adenocarcinomas and its treatment.

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Characterization of mucin-type oligosaccharides with the sialyl-Le(a) structure from human colorectal adenocarcinoma cells

Biochemical and Biophysical Research Communications

Aug 15, 1991

H KitagawaI Yamashina

PMID: 1908236

DOI: 10.1016/0006-291x(91)91053-f

Abstract

Oligosaccharides with the sialyl-Le(a) structure have been isolated on an affinity column of a monoclonal antibody, MSW 113, from mucin-type glycoproteins derived from the surfaces of SW 1116 and LS 180 cells, and their secretions. The oligosaccharides were polydisperse with respect to ...read more

Mentioned in this Paper

poly-N-acetyllactosamine
Monoclonal Antibodies
GLB1
Keratan-sulfate endo-1,4-b-galactosidase
Mucin-1 protein
Glycoproteins
Malignant Tumor of Colon
Citrobacter freundii
Adenocarcinoma of Large Intestine
Blood-group-substance endo-1,4-b-galactosidase

Similar Papers Found In These Feeds

Colon Adenocarcinoma

Approximately 95% of all colon cancers are colon adenocarcinomas, which are associated with a significant reduction in or loss of goblet cells. Here is the latest research on colon adenocarcinomas and its treatment.

Related Papers

Paper Details
References
  • References2
  • Citations3
1
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