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Characterization of Novel 18 F-Labeled Phenoxymethylpyridine Derivatives as Amylin Imaging Probes

Molecular Pharmaceutics

Nov 9, 2018

Hiroyuki WatanabeHideo Saji

Abstract

Deposition of islet amyloid consisting of amylin constitutes one of pathological hallmarks of type 2 diabetes mellitus (T2DM), and it may be involved in the development and progression of T2DM. However, the details about the relationship between the deposition of islet amyloid and the p...read more

Mentioned in this Paper

Diabetes Mellitus, Non-Insulin-Dependent
Study
In Vivo
Bioassay, In Vivo
Derivatives
APP protein, human
Benign Tumor of Pancreas
Mouse Pancreas
Amyloid Deposition
6-fluoropyridoxamine 5'-phosphate
1
4
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Characterization of Novel 18 F-Labeled Phenoxymethylpyridine Derivatives as Amylin Imaging Probes

Molecular Pharmaceutics

Nov 9, 2018

Hiroyuki WatanabeHideo Saji

PMID: 30407835

DOI: 10.1021/acs.molpharmaceut.8b00756

Abstract

Deposition of islet amyloid consisting of amylin constitutes one of pathological hallmarks of type 2 diabetes mellitus (T2DM), and it may be involved in the development and progression of T2DM. However, the details about the relationship between the deposition of islet amyloid and the p...read more

Mentioned in this Paper

Diabetes Mellitus, Non-Insulin-Dependent
Study
In Vivo
Bioassay, In Vivo
Derivatives
APP protein, human
Benign Tumor of Pancreas
Mouse Pancreas
Amyloid Deposition
6-fluoropyridoxamine 5'-phosphate
1
4

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