Characterization of Oligofructose-Induced Acute Rumen Lactic Acidosis and the Appearance of Laminitis in Zebu Cattle

Animals : an Open Access Journal From MDPI
Rejane Santos SousaEnrico Lippi Ortolani

Abstract

The objective of this study was to characterize oligofructose-induced acute rumen lactic acidosis and its consequences in zebu cattle. We used 29 Nellore heifers which were submitted to experimental induction of laminitis by oligofructose excess. During the induction period, the animals underwent clinical examination, including laminitis diagnosis (hoof pressure testing and locomotion score) and blood and ruminal fluid sampling every six hours (over the initial 24 h) and every 12 h (up to 72 h), after the highest dose. Almost half of the animals (48.1%) required treatment with bicarbonate and saline to correct metabolic acidosis and dehydration. Due to this treatment, the animals were analyzed in treated (n = 13) and non-treated (n = 14) groups. The induction model promoted marked reduction in rumen pH, rumen anaerobiosis, carbon dioxide pressure, and increase in rumen lactate, blood osmolarity, and cortisol concentration. The animals treated had lower values of rumen pH and marked dehydration, evidenced by the increase in globular volume and serum urea. The clinical condition caused by excess oligofructose is severe, with the differential of the appearance of ephemeral fever and respiratory compensation against systemic acidos...Continue Reading

References

Apr 1, 1988·The Veterinary Quarterly·J A LohuisA S van Miert
Aug 1, 1965·Australian Journal of Biological Sciences·V J Williams, D D Mackenzie
Aug 21, 1993·The Veterinary Record·S S SinghR D Murray
May 1, 1997·Journal of Dairy Science·J E Nocek
Feb 17, 1998·Journal of Animal Science·F N OwensD R Gill
Aug 21, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·C Graham, N L Simmons
Sep 18, 2004·Journal of Dairy Science·M B ThoefnerPia H Andersen
Jan 20, 2007·Physiology & Behavior·Pierre MormèdeIsabelle Veissier
May 23, 2007·Journal of Dairy Science·T G Nagaraja, E C Titgemeyer
Mar 11, 2008·The Veterinary Journal·Jan C PlaizierB W McBride
Jan 24, 2009·Journal of Dairy Science·Anne Mette DanscherM B Thoefner
Jan 12, 2010·Journal of Dairy Science·Anne Mette DanscherO Wattle
Jul 18, 2015·Acta Veterinaria Scandinavica·Anne Mette DanscherJan C Plaizier
Aug 6, 2015·Journal of Veterinary Science·Hedie A BustamanteMarianne P Werner
Jan 11, 2018·BMC Veterinary Research·Leonardo Frasson ReisEnrico Lippi Ortolani

Citations

Dec 31, 2020·Animals : an Open Access Journal From MDPI·Natalia Sato MinamiEnrico Lippi Ortolani

Related Concepts

Acidosis
Acidosis, Lactic
Anaerobiosis
Bicarbonates
Blood
Carbon Dioxide
Dehydration
Diagnosis
Ephemeral Fever
Hydrocortisone

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