PMID: 9193155Jan 1, 1997Paper

Characterization of Purkinje cells in the goldfish cerebellum during eye movement and adaptive modification of the vestibulo-ocular reflex

Progress in Brain Research
A M PastorR Baker

Abstract

The discharge characteristics of Purkinje cells were analyzed in the goldfish cerebellum during eye movement and adaptation of the vestibulo-ocular reflex (VOR). Purkinje cells, identified by the simultaneous recording of complex and simple spikes, were recorded in the cerebellar area where electrical microstimulation elicited ipsiversive horizontal eye movements. Simple spikes of Purkinje cells displayed signals related to head and/or eye velocity as determined independently during either VOR suppression or optokinetic stimulation, respectively. Head velocity-only Purkinje cells (12%) increased their firing rate in relationship to ipsilateral head movements. Two types of eye velocity-only Purkinje cells (28%) were found that responded either in phase with ipsi- (16%) or contralateral (12%) eye movement, respectively. Purkinje cells combining both eye and head velocity (60%) were classified into two groups according to their preferred direction for eye movement. Eye velocity signals either added to (18%) or subtracted from (42%) head velocity during all visuo-vestibular interactions. Short term adaptive changes of the VOR were induced by oscillating goldfish in a moving visual surround that modified the ratio of eye to head vel...Continue Reading

Citations

Mar 29, 2001·Physiological Reviews·G Bosco, R E Poppele
Feb 3, 2015·Brain and Behavior·Akira KatohJennifer L Raymond
Jul 1, 2010·The Journal of Comparative Neurology·Patricia Herrera-PérezJosé A Muñoz-Cueto
Apr 24, 2014·ELife·Rhea R KimpoJennifer L Raymond
Jul 17, 1999·Annals of the New York Academy of Sciences·H SuwaR Baker
Feb 11, 2011·Developmental Neurobiology·Masahiko Hibi, Takashi Shimizu
Oct 29, 2013·Nature Neuroscience·T D Barbara Nguyen-VuJennifer L Raymond

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