Characterization of Robust and Free-Standing 2D-Nanomembranes of UV-Polymerized Diacetylene Lipids

Langmuir : the ACS Journal of Surfaces and Colloids
Roland HillmannDario Anselmetti

Abstract

Free-standing lipid membranes are promising as artificial functional membrane systems for application in separation, filtration, and nanopore sensing. To improve the mechanical properties of lipid membranes, UV-polymerized lipids have been introduced. We investigated free-standing as well as substrate-supported monolayers of 1-palmitoyl-2-(10,12-tricosadiynoyl)- sn-glycero-3-phosphoethanolamine (PTPE) and 1,2-bis(10,12-tricosadiynoyl)- sn-glycero-3-phosphocholine (DiynePC) and characterized them with respect to their structure, morphology, and stability. Using helium ion microscopy (HIM), we were able to visualize the integrity of the lipid 2D-nanomembranes spanning micrometer-sized voids under high-vacuum conditions. Atomic force microscopy (AFM) investigations under ambient conditions revealed formation of intact and robust pore-spanning 2D-nanomembranes up to 8 × 2 μm2 in size. Analysis by attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) verified a distinct reduction of signal at 2143 cm-1 from diacetylene groups in the 2D-nanomembranes after UV-polymerization. Further high-resolution AFM investigations of unpolymerized lipid monolayers revealed a well-ordered two-dimensional network, when depos...Continue Reading

References

Nov 26, 1996·Proceedings of the National Academy of Sciences of the United States of America·J J KasianowiczD W Deamer
Jun 23, 1998·Quarterly Reviews of Biophysics·L K Tamm, S A Tatulian
Sep 28, 2004·Nature Materials·Chaoyang JiangVladimir V Tsukruk
Jan 12, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Guangzhao MaoHelmuth Möhwald
Sep 30, 2005·Nature·Motomu Tanaka, Erich Sackmann
Oct 25, 2007·Chemical Communications : Chem Comm·Mary A Reppy, Bradford A Pindzola
Feb 29, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Jeffrey A Nye, Jay T Groves
Jul 26, 2008·Nature Nanotechnology·Cees Dekker
Dec 11, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Takashi OkazakiKenichi Morigaki
Dec 23, 2008·Proceedings of the National Academy of Sciences of the United States of America·Tom Z ButlerJens H Gundlach
Jan 27, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Yair KaufmanViatcheslav Freger
Aug 12, 2010·Nano Letters·Christopher A MerchantMarija Drndić
Aug 20, 2011·Biochimica Et Biophysica Acta·Eugene SerebryanyElsa C Y Yan
Sep 20, 2011·Nature Nanotechnology·Bala Murali Venkatesan, Rashid Bashir
Feb 19, 2014·Advanced Materials·Min AiAndré Beyer
May 23, 2014·Nature Chemistry·Stephen SchrettlHolger Frauenrath
Aug 21, 2014·Angewandte Chemie·Dario Anselmetti, Armin Gölzhäuser
Sep 23, 2014·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Maciej Roman, Malgorzata Baranska
Mar 7, 2015·Genomics, Proteomics & Bioinformatics·Yanxiao FengChunlei Du
Nov 12, 2016·Physical Chemistry Chemical Physics : PCCP·Elisseos VerveniotisMasakazu Aono
Jan 21, 2017·Analytical Chemistry·Wenqing ShiLane A Baker

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Citations

Jun 4, 2020·Biomimetics·Zoran Jakšić, Olga Jakšić
Dec 10, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·ZhangFei SuJacek Lipkowski
Jun 28, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Dominic GilzerTilman Kottke
Jan 25, 2019·The Journal of Physical Chemistry. B·Gesche GrafAlfred Blume

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