PMID: 9650954Jul 3, 1998Paper

Characterization of serologically nontypeable Actinobacillus actinomycetemcomitans isolates

Journal of Clinical Microbiology
Susanna PajuS Asikainen

Abstract

Our previous studies have shown that Actinobacillus actinomycetemcomitans isolates of a given arbitrarily primed PCR (AP-PCR) genotype belong to the same serotype (of serotypes a through e). In the present study we investigated whether the AP-PCR genotypes of nonserotypeable A. actinomycetemcomitans isolates match those of the serotypeable isolates. The isolates were additionally characterized by restriction analysis of the apaH PCR amplification products. The material included 75 nonserotypeable and 18 serotypeable A. actinomycetemcomitans isolates from 34 epidemiologically unrelated subjects. The serotypeable isolates were obtained from subjects who also harbored nonserotypeable isolates. Eight AP-PCR genotypes were distinguished among the isolates; six genotypes matched those detected in our previous studies, whereas two genotypes were new. Intraindividually, the A. actinomycetemcomitans isolates produced identical AP-PCR banding patterns, regardless of whether they were serotypeable or nonserotypeable, in 22 of 23 subjects participating with multiple isolates. AP-PCR genotype 3, corresponding to serotype c, was by far the most common among the nonserotypeable isolates (62% of subjects). Results obtained with the apaH restri...Continue Reading

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Citations

Aug 26, 2004·Oral Microbiology and Immunology·O FujiseC Chen
May 10, 2007·Oral Microbiology and Immunology·K ThihaI Ishikawa
Jul 31, 2003·Journal of Periodontology·Başak DoğanSirkka Asikainen
Jun 12, 2010·Molecular Oral Microbiology·K TakadaM Hirasawa
Feb 1, 2018·Journal of Clinical Periodontology·Milla PietiäinenPirkko J Pussinen
Feb 9, 2010·Journal of Dental Research·E KanasiS Asikainen
Apr 28, 2001·Journal of Clinical Microbiology·N SuzukiT Koga

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