Characterization of sprays for thermo-stabilized pneumatic nebulizer

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
M OchowiakA Gościniak

Abstract

The research presents the nebulizer spray chamber temperature controller responsible for controlling temperature of aerosol produced as a result of nebulizing process. The motivation to make an attempt to improve modern pneumatic devices was the shortage of this kind of apparatuses on the market allowing the production of thermos aerosol. A designed temperature controlling system for pneumatic nebulizers aims at increasing and stabilizing temperature of produced aerosols and increasing aerosol therapy safety. The system is intended for producing aerosol in the process of pneumatic nebulization with the temperature similar to that of the human body. Experiments that were carried out confirmed good performance of the device. It was proved that with the increase of temperature the amount of big droplets fall and the entire spectrum of the droplet diameter moves towards smaller droplet diameter values. Reduction of liquid viscosity related to the increase of temperature leads to the reduction of droplet diameter and, as a result, the reduction of the Sauter mean diameter value.

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Citations

Jul 25, 2017·Drug Development and Industrial Pharmacy·Marek OchowiakSylwia Włodarczak

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