PMID: 9527516Jan 1, 1997Paper

Characterization of Streptomyces sp. strain DRS-1 and its ampicillin transformation product

Folia Microbiologica
D RoyA C Ghosh

Abstract

Incubation of ampicillin with whole cells of Streptomyces sp. DRS-1 resulted in accumulation of four compounds different from ampicillin. One of them was isolated, purified and partially characterized. On the basis of spectroscopic characteristics, RF value and antibacterial activity the compound was identified as cephalexin. It could also be obtained from ampicillin by using crude protein extract of the strain.

References

Dec 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·M YoshidaA L Demain
May 17, 1976·Biochemical and Biophysical Research Communications·M Kohsaka, A L Demain
May 7, 1971·The Journal of Organic Chemistry·R R ChauvetteG W Huffman
Jan 1, 1964·Journal of Clinical Pathology·S T BUTTERWORTH

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