PMID: 11900956Mar 20, 2002Paper

Characterization of the carrier state in porcine reproductive and respiratory syndrome virus infection

Veterinary Microbiology
Dennis C HorterJ J Zimmerman

Abstract

Porcine reproductive and respiratory syndrome (PRRS) virus infection results in clinically normal, but persistently infected animals. An understanding of the carrier state is necessary for prevention, control and/or elimination of PRRS virus. The objective of this experiment was to estimate the proportion of PRRS virus carriers over time and determine which combination of sample and diagnostic assay could most effectively identify persistently infected animals. Sixty 3-week-old pigs were inoculated with PRRS virus ATCC VR-2332 and followed for up to 105 days post-inoculation (PI). Sixty age-matched animals served as uninoculated controls. Samples (serum, peripheral blood leukocytes, oropharyngeal scrapings, tonsil, bronchoalveolar lavage, lung tissue and tracheobronchial lymph nodes) were collected periodically and tested for evidence of PRRS virus infection by virus isolation (VI), swine bioassay and reverse transcriptase-nested polymerase chain reaction (RT-nPCR). The PRRS virus-specific antibody response was monitored with a commercial enzyme-linked immunosorbent assay (ELISA). Overall, PRRS virus was found in 51 of the 59 (84%) necropsied animals by VI or swine bioassay between 63 and 105 days PI, including 10 of the 11 (91...Continue Reading

References

Apr 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J E CollinsH S Joo
Jul 1, 1991·The Veterinary Quarterly·G WensvoortF Wagenaar
Sep 15, 1980·Experientia·K E Rowson
Jul 1, 1995·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K J YoonK B Platt
Aug 17, 1994·Molecular and Cellular Biochemistry·A M WuA Herp
Jan 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·K D RossowJ E Collins
Jul 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·G W StevensonK K Keffaber
Jun 5, 1993·The Veterinary Record·A Higgins
Oct 1, 1995·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J Christopher-HenningsD A Benfield
Apr 1, 1996·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·W L MengelingA C Vorwald
Apr 1, 1997·Veterinary Microbiology·R W WillsE A Nelson
Feb 26, 2000·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·E A WagstromJ J Zimmerman
Mar 31, 2001·Journal of the American Veterinary Medical Association·UNKNOWN AVMA Panel on Euthanasia. American Veterinary Medical Association
Apr 6, 2001·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J Christopher-HenningsE A Nelson

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Citations

Jan 5, 2014·The Journal of Microbiology·Sang-Im Yun, Young-Min Lee
Oct 19, 2007·Journal of Virology·Prasad MulupuriMichael P Murtaugh
Feb 7, 2008·Emerging Infectious Diseases·Guang-Zhi TongHua-Ji Qiu
Oct 28, 2004·Veterinary Immunology and Immunopathology·Udeni B R Balasuriya, N James MacLachlan
Oct 28, 2004·Veterinary Immunology and Immunopathology·Sang-Myeong LeeSteven B Kleiboeker
May 30, 2006·Theriogenology·Jenny G Cho, Scott A Dee
Jun 5, 2015·Journal of the American Veterinary Medical Association·Andres M PerezRobert B Morrison
Jun 20, 2012·Current Opinion in Virology·Ranjni J ChandRaymond R R Rowland
Sep 1, 2005·Virology·Sang-Myeong Lee, Steven B Kleiboeker
Oct 7, 2008·Veterinary Immunology and Immunopathology·R M MolinaJ J Zimmerman
Jul 3, 2018·Transboundary and Emerging Diseases·Ramón Molina-BarriosJeffrey Zimmerman
Feb 23, 2017·Scientific Reports·Thibaud PorphyreMark E J Woolhouse
Jan 29, 2019·Transboundary and Emerging Diseases·Mercy RamírezHermelinda Rivera
Jul 28, 2021·Animal : an International Journal of Animal Bioscience·A Doeschl-WilsonS J More
Nov 9, 2021·Transboundary and Emerging Diseases·Magnus R CamplerAndréia G Arruda

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