PMID: 11907392Mar 22, 2002Paper

Characterization of the cerebral blood flow response to balloon deflation after temporary internal carotid artery test occlusion

Journal of Neurosurgical Anesthesiology
Dhanesh K GuptaN Ostapkovich

Abstract

The authors tested the hypothesis that cerebral blood flow (CBF) would increase after acute and relatively brief internal carotid artery (ICA) test occlusion, and examined the relationship of the postdeflation CBF to the development of neurologic symptoms. In 16 patients undergoing ICA test occlusion with deliberate hypotension, the authors measured intracarotid 133Xe CBF at baseline, occlusion, and deflation. Four patients developed neurologic symptoms during occlusion. As positive controls, 11 other patients received intracarotid verapamil or papaverine before deflation as part of another protocol. Balloon occlusion was 23.1 +/- 10.5 minutes (mean +/- standard deviation) in duration. At 1.3 +/- 1.6 minutes after balloon deflation, there was a trend (12 +/- 31%) for CBF to increase (48 +/- 9 mL/100 g/min versus 53 +/- 17 mL/100 g/min, P =.15), and a 16 +/- 27% decrease in cerebrovascular resistance (CVR; 2.1 +/- 0.6 mm Hg/100 g/min/mL versus 1.7 +/- 0.6 mm Hg/100 g/min/mL, P =.03) compared with baseline values. By comparison, patients who received a intracarotid dilator demonstrated a 53 +/- 55% increase in CBF (48 +/- 10 mL/100/min versus 70 +/- 23 mL/100 g/min, P = .007) and a 33 +/- 31% decrease in CVR (2.2 +/- 0.6 mm Hg/10...Continue Reading

References

Jul 1, 1992·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·G Florence, J Seylaz
Dec 1, 1991·Journal of Neurosurgery·R MacfarlaneH A Kontos
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May 18, 1999·Journal of Neurology, Neurosurgery, and Psychiatry·R S MarshallW L Young

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Citations

Mar 4, 2003·Pediatric Radiology·Craig B GlaibermanDanielle K B Boal
Aug 30, 2008·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Bernhard Schaller
Feb 8, 2005·Neurosurgery Clinics of North America·Richard J ParkinsonH Hunt Batjer
Aug 13, 2014·Anesthesiology Clinics·Andrey ApinisJonathan Leff
Oct 31, 2011·The Neuroradiology Journal·T HassanM N Elwany

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