Characterization of the complete genome of influenza A (H5N1) virus isolated during the 2006 outbreak in poultry in India.

Virus Genes
Koninika RayAkhilesh C Mishra

Abstract

An outbreak of highly pathogenic avian influenza A (H5N1) virus in poultry was reported from Nandurbar and Jalgaon districts of Maharashtra and adjoining areas of Uchhal in Gujarat and Burhanpur in Madhya Pradesh in India from January to April, 2006. In the present study, the full genome of two previously uncharacterized strains of H5N1 viruses isolated at the National Institute of Virology (NIV), Pune, from post-mortem tissues of chicken collected from Navapur, Nandurbar district during the outbreak, has been presented. All the genes belong to clade 2.2 of the Z genotype and are close to the 2006 isolates from Iran, Afghanistan, Mongolia, Italy, and Krasnodar. In a study reported earlier, based on the partial gene sequences of HA, the authors (Pattnaik et al.) hypothesized that the viruses in Jalgaon and Navapur, causing outbreaks 12 days apart, were introduced at different times from different sources. However, our Navapur isolates are closer to the isolate reported from Jalgaon than that from Navapur. Molecular markers suggest that the isolates are sensitive to both drugs Oseltamivir and Amantadine. Amino acid residues responsible for pathogenesis, glycosylation, and receptor binding have also been discussed. The relationshi...Continue Reading

References

Nov 1, 1991·The Journal of Infectious Diseases·C SweetA J Hay
Dec 21, 1989·The New England Journal of Medicine·F G HaydenW Soo
Jun 1, 1989·The Journal of Infectious Diseases·W J BeanR G Webster
Dec 5, 1993·Journal of Molecular Biology·A Sali, T L Blundell
Jan 1, 1996·Methods in Enzymology·D G HigginsT J Gibson
Oct 24, 2000·Journal of Virology·J M KatzK Subbarao
Jan 25, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Guy BoivinHarold Bernatchez
Jan 29, 2002·Archives of Virology·E HoffmannD R Perez
Sep 27, 2003·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Hiroshi SuzukiIsamu Sato
Apr 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Mikhail N MatrosovichHans-Dieter Klenk
Jul 21, 2004·Briefings in Bioinformatics·Sudhir KumarMasatoshi Nei
Jan 22, 2005·The Journal of General Virology·Pilaipan PuthavathanaPathom Sawanpanyalert
Dec 2, 2005·Emerging Infectious Diseases·UNKNOWN World Health Organization Global Influenza Program Surveillance Network
Dec 13, 2005·Proceedings of the National Academy of Sciences of the United States of America·G GabrielJ Stech
Jan 20, 2006·Reproduction in Domestic Animals = Zuchthygiene·J M Morrell
Apr 22, 2006·Science·Björn OlsenRon A M Fouchier
Aug 31, 2006·Antimicrobial Agents and Chemotherapy·M A Rameix-WeltiN Naffakh
Nov 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·G J D SmithY Guan
Jun 8, 2007·Emerging Infectious Diseases·Steven L SalzbergIlaria Capua
Jul 1, 2007·Influenza and Other Respiratory Viruses·UNKNOWN Global Influenza Programme

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Citations

Feb 25, 2009·Virology Journal·Akhilesh C MishraSadhana S Kode
Jun 3, 2014·International Journal of Health Geographics·Ruiyun LiBing Xu
Apr 5, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Jayati MullickAkhilesh C Mishra
Dec 1, 2019·Tropical Medicine and Infectious Disease·Sukanta ChowdhuryMohammed Ziaur Rahman
Jan 1, 2012·Proceedings of the National Academy of Sciences, India. Section B·Kaushik Bharati, Sudhanshu Vrati

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