PMID: 6162152Dec 11, 1980Paper

Characterization of the Escherichia coli 23S Ribosomal RNA region associated with ribosomal protein L1. Evidence for homologies with the 5'-end region of the L11 operon

Nucleic Acids Research
C BranlantJ P Ebel

Abstract

The results previously obtained upon studying the L1-23S RNA complex by the fingerprint technique have been reexamined in the light of new data on 23S RNA primary structure. The 23S RNA region that remains associated with the L1 ribosomal protein after RNase digestion of the synthetic complex lies between nucleotides 2067 and 2235 from the 5'-end of the molecule. This region contains a m7G near to the 5'-end and possesses a high degree of mutability in E. coli. Three different sequences were observed in E. coli MRE 600. All three sequences differ in two positions relative to the corresponding sequence in rrnB cistron from E. coli K12. Striking homology is observed between the 23S RNA region associated with protein L1 and the 5'-part of L11 operon. This observation supports the model of feedback regulation of r-proteins synthesis proposed by Yates et al. (PNAS, 77, 1837) and strongly suggests that the region of 23S RNA located between positions 2155 and 2202 is essential for the binding of protein L1.

References

Aug 15, 1977·European Journal of Biochemistry·F HernándezJ P Ballesta
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·L E PostP P Dennis
Nov 1, 1979·FEBS Letters·C BranlantJ P Ebel
Nov 15, 1976·European Journal of Biochemistry·C BranlantJ P Ebel
Sep 15, 1974·Journal of Molecular Biology·R A GarretR A Zimmermann
Jun 27, 1970·Nature·S Mizushima, M Nomura
Jan 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J BrosiusH F Noller
Apr 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J L YatesM Nomura

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Citations

Feb 28, 2009·Advances in Applied Microbiology·Wolfgang Schumann
Feb 7, 1982·Journal of Theoretical Biology·C H Clarke
May 5, 1985·Journal of Molecular Biology·A E ChakerianK S Matthews
Apr 1, 1983·Journal of Bacteriology·G D Parsons, G A Mackie

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