PMID: 7422356Aug 1, 1980Paper

Characterization of the exposed carbohydrates on the surface membrane of adult Schistosoma mansoni by analysis of lectin binding

Parasitology
A J Simpson, S R Smithers

Abstract

The surface architecture of adult male Schistosoma mansoni was explored using a range of lectins with differing carbohydrate specificites. Highest specific binding was achieved with concanavalin A and the agglutinin of molecular weight 60000 from Ricinus communis; the binding of wheat germ agglutinin was mostly non-specific. Small amounts of peanut agglutinin and soybean agglutinin binding were observed and the binding of these lectins was increased by pre-treating the parasite with neuraminidase. The fucose binding protein of Lotus tetragonolobus failed to bind. These results indicate that mannose and/or glucose, galactose, N-acetylglucosamine, N-acetyl-galactosamine and sialic acid are exposed on the surface of the adult male schistosome.

References

Dec 1, 1978·Experimental Parasitology·K D MurrellD A Dean
Jun 1, 1973·Experimental Parasitology·P C Stein, R D Lumsden
Jul 16, 1974·Biochemistry·M E Pereira, E A Kabat
Oct 1, 1974·Carbohydrate Research·M E PereiraN Sharon
Apr 8, 1974·Biochimica Et Biophysica Acta·S G Nathenson, S E Cullen
Aug 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·S Kornfeld, R Kornfeld

Citations

Nov 1, 1981·Molecular and Biochemical Parasitology·A J SimpsonW H Evans
Oct 1, 1983·Molecular and Biochemical Parasitology·S M RobertsR A Wilson
Mar 1, 1984·Molecular and Biochemical Parasitology·M Philipp, F D Rumjaneck
Aug 1, 1985·Molecular and Biochemical Parasitology·A N MacGregorJ R Kusel
Jan 15, 1987·Molecular and Biochemical Parasitology·M V Rogers, D J McLaren
May 15, 1989·Molecular and Biochemical Parasitology·A N MacGregor, J R Kusel
Nov 1, 1990·Molecular and Biochemical Parasitology·C A Rivera-Marrero, R D Cummings
Mar 13, 1998·Molecular and Biochemical Parasitology·C A RedmanJ R Kusel
Jul 15, 1998·Molecular and Biochemical Parasitology·E T MarquesM Strand
Aug 1, 1986·Journal of Chemical Ecology·M A Haseeb, L K Eveland
Jul 1, 1993·Membrane Biochemistry·F H Pujol, I M Cesari
Feb 1, 1982·Experimental Parasitology·A J Simpson, D J McLaren
Oct 11, 1991·Experimental Parasitology·D E HillJ F Urban
Dec 1, 1984·Parasitology·G C Coles
Sep 1, 1987·Journal of Helminthology·K MasoodV M Srivastava
Mar 28, 2003·The Journal of Parasitology·Cecilia CasaravillaCarlos Carmona
Feb 20, 2007·Memórias do Instituto Oswaldo Cruz·A C A MattosP M Z Coelho
Jan 1, 1985·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·N P Robertson, G D Cain
May 1, 1984·Infection and Immunity·R F Melhem, P T LoVerde

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