Characterization of the gene encoding carbonic anhydrase I from the pigtail macaque

P J HopkinsR E Tashian


The structure of the gene encoding carbonic anhydrase I (CA I) was determined for the pigtail macaque Macaca nemestrina. When the deduced amino-acid sequence was compared with those of five other primates, four non-primate mammals and a turtle, seven residues were found to be unique and invariant to all of the CA I sequences. A scheme is presented for the probable evolutionary order of the six polymorphic nucleotide changes found in the coding regions of the CA I locus of pigtail macaques.


Jun 1, 1989·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·R E Tashian
Jun 11, 1987·Nucleic Acids Research·J C MontgomeryD Hewett-Emmett
Sep 16, 1980·Biochemical and Biophysical Research Communications·D HenrikssonR E Tashian
Jan 22, 1982·Nucleic Acids Research·S M Mount


Oct 24, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Andrew J EsbaughK M Gilmour

Related Concepts

DNA Sequence
Carbonate Dehydratase
DNA, Double-Stranded
Biological Evolution
Macaca nemestrina
Homologous Sequences, Nucleic Acid
Mouse, Swiss

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