Characterization of the genetic factors affecting quinolizidine alkaloid biosynthesis and its response to abiotic stress in narrow-leafed lupin (Lupinus angustifolius L.)

Plant, Cell & Environment
Karen M FrickKaram B Singh

Abstract

Quinolizidine alkaloids (QAs) are toxic secondary metabolites that complicate the end use of narrow-leafed lupin (NLL; Lupinus angustifolius L.) grain, as levels sometimes exceed the industry limit for its use as a food and feed source. The genotypic and environmental influences on QA production in NLL are poorly understood. Here, the expression of QA biosynthetic genes was analysed in vegetative and reproductive tissues of bitter (high QA) and sweet (low QA) accessions. It was demonstrated that sweet accessions are characterized by lower QA biosynthetic gene expression exclusively in leaf and stem tissues than bitter NLL, consistent with the hypothesis that QAs are predominantly produced in aerial tissues and transported to seeds, rather than synthesized within the seed itself. This analysis informed our identification of additional candidate genes involved in QA biosynthesis. Drought and temperature stress are two major abiotic stresses that often occur during NLL pod set. Hence, we assessed the effect of drought, increased temperature, and their combination, on QA production in three sweet NLL cultivars. A cultivar-specific response to drought and temperature in grain QA levels was observed, including the identification of a...Continue Reading

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Citations

Feb 23, 2019·Journal of Experimental Botany·Leonor MargalhaElena Baena-González
Feb 20, 2019·Annals of Botany·Germán WiesGustavo Ángel Maddonni
Feb 6, 2020·Plant Foods for Human Nutrition·Paola Cortés-AvendañoRitva Repo-Carrasco-Valencia
Jul 23, 2019·Journal of Experimental Botany·Sophie Lisa OtterbachFernando Geu-Flores
Feb 20, 2019·International Journal of Molecular Sciences·Eleni M AbrahamDimitrios Vlachostergios
Aug 15, 2019·Journal of Applied Genetics·Sandra Rychel, Michał Książkiewicz

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