PMID: 6166690Feb 1, 1981Paper

Characterization of the RT2 antigens of the rat erythrocyte membrane

Journal of Immunogenetics
D N MisraH W Kunz

Abstract

Haemagglutination inhibition studies using isolated membrane components from rat red blood cells showed that the activity of the major antigenic system RT2 was contained exclusively in the glycoprotein fraction and confirmed immunochemically the existence of two alleles, RT2 a and RT2 b. The SDS-PAGE analysis of the membrane showed two interconvertible glycoproteins of apparent molecular weight 72,000 and 36,000, and the higher molecular weight component appeared to be a dimer of the lower molecular weight one. Analysis of the various membrane preparations after 125I-labelling showed that the glycoproteins existed in at least two molecular species on the surface of the red cells and that one species was more readily radio-iodinated and dimerized than the other. The RT2 antigenic specificities were preferentially associated with this component.

References

Dec 1, 1978·Journal of Immunogenetics·H W Kunz, T J Gill
Feb 28, 1978·Biochemical and Biophysical Research Communications·P J Fraker, J C Speck
Aug 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·M Tomita, V T Marchesi
Jul 8, 1975·Biochemical and Biophysical Research Communications·H FurthmayrV T Marchesi
Jun 19, 1973·Biochemical and Biophysical Research Communications·L S Marton, L E Garvin
Apr 26, 1974·Nature·M MorrisonS I Choi
Jul 10, 1974·Biochemical and Biophysical Research Communications·J K Tuech, M Morrison
Oct 2, 1967·Biochimica Et Biophysica Acta·G J Nelson
Jan 1, 1963·Archives of Biochemistry and Biophysics·J T DODGED J HANAHAN
May 3, 1962·Annals of the New York Academy of Sciences·R D OWEN
May 3, 1962·Annals of the New York Academy of Sciences·J PALM

❮ Previous
Next ❯

Citations

Jun 1, 1995·Human Nature : an Interdisciplinary Biosocial Perspective·J Carroll
Dec 1, 1986·Photochemistry and Photobiology·A R GrossmanP B Conley
Jan 5, 2002·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·E Humann-Ziehank, K Bickhardt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.