PMID: 6973558Sep 1, 1980Paper

Characterization of three different human T cell membrane antigens, two being present on T lymphocyte subpopulations

Human Immunology
R BillingP I Terasaki

Abstract

Heteroantisera were raised in rabbits to thymocytes, HSB2 cells, and Sezary cells. Following absorption with Ia-positive leukemia cells, these sera appeared to be specific for different T cell antigens. Both the anti-HSB2 and the anti-Sezary sera reacted with approximately 50% and the antithymocyte serum with 100% of normal peripheral blood T lymphocytes. None of the sera reacted with B cells. The apparent molecular weights of the antigens being detected were determined by immunoprecipitation followed by SDS polyacrylamide gel electrophoresis. A dimer of 170,000 daltons consisting of two similar 85,000-dalton polypeptide chains was immunoprecipitated by the anti-HSB2 serum whereas single polypeptides of 53,000 and 64,000 daltons were immunoprecipitated by the anti-Sezary and antithymocyte sera, respectively.

References

Aug 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·E L ReinherzS F Schlossman
Apr 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·T A SpringerD Mann
Oct 25, 1974·Nature·I RoystonJ S Pagano

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Citations

Jul 2, 1981·The New England Journal of Medicine·J H FitchenM J Cline
Apr 1, 1987·Journal of Immunogenetics·R L DawkinsM S Stuckey
Apr 1, 1987·Journal of Immunogenetics·V StenszkyN R Farid
Jan 1, 1983·Immunological Reviews·A SvejgaardL P Ryder
May 1, 1981·The British Journal of Ophthalmology·R B Nussenblatt, K K Mittal
Aug 1, 1988·World Journal of Surgery·O OzakiY Hosoda
Jan 29, 1983·British Medical Journal·M J GarleppF T Christiansen
Apr 1, 1983·Scandinavian Journal of Haematology·H J van der ReijdenA E von dem Borne

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