Characterization of Unique Lens Morphology in a Cohort of Children with Familial Exudative Vitreoretinopathy.

Current Eye Research
Dongmei QiTao Yu

Abstract

Purpose: To characterize the lens morphology and to measure the clinical features of familial exudative vitreoretinopathy (FEVR) in children. Methods: Unique lens changes were observed in a cohort of children with FEVR from March 2015 to November 2017 using slit lamp examination and all the patients underwent cycloplegic refraction, ultrasound A and B, keratometry and fundus fluorescein angiography. Results: Twelve eyes of eight children with FEVR had unique lens changes. The contraction of the posterior capsule caused unique lens changes resulting in myopia in nine eyes of six children and astigmatism in eight eyes of five children. Retinal lesions in the affected eyes were all stage 1 to 2. Six eyes of three patients underwent lensectomy and intraocular lens implantation due to high anisometropia which could not be corrected by conventional optical correction. During lensectomy, the opacification in the posterior capsule was found to be due to the fibrous membrane that protruded into the anterior vitreous and not due to lens opacification. Three patients had bilateral lensectomy, in two of whom significant macular involvement was observed in one eye and in one of whom significant macular involvement was observed in both eyes....Continue Reading

References

Oct 1, 1969·American Journal of Ophthalmology·V G Criswick, C L Schepens
Sep 23, 1982·Documenta Ophthalmologica. Advances in Ophthalmology·C E van Nouhuys
Jan 1, 1980·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·H Laqua
Aug 13, 2002·Nature Genetics·Johane RobitailleMark E Samuels
Sep 4, 2004·American Journal of Human Genetics·Xiaodong JiaoJ Fielding Hejtmancik
Feb 18, 2010·American Journal of Human Genetics·James A PoulterCarmel Toomes
May 30, 2013·Proceedings of the National Academy of Sciences of the United States of America·Rob W J CollinFrans P M Cremers
Aug 9, 2017·Investigative Ophthalmology & Visual Science·Johannes BirtelPeter Charbel Issa

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Citations

Apr 29, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Wenmin SunQingjiong Zhang

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