Characterizing opioid use in a US population with migraine: Results from the CaMEO study.

Neurology
Richard B LiptonTodd J Schwedt

Abstract

To determine the prevalence of and risk factors associated with opioid use in the treatment of migraine, we examined demographics and clinical characteristics of 867 individuals who reported using opioids for the treatment of migraine. We analyzed data from the CaMEO study (Chronic Migraine Epidemiology and Outcomes), a cross-sectional, longitudinal, Internet study, to compare sociodemographics, clinical characteristics, and migraine burden/disability of opioid users vs nonusers. Covariates were entered as categorical or continuous variables. Factors associated with opioid use were identified using nested, multivariable binary logistic regression models. Of 2,388 respondents with migraine using prescription medications for acute treatment, 36.3% reported that they currently used or kept on hand opioid medications to treat headaches. Current opioid users had significantly more comorbidities, greater headache-related burden, and poorer quality of life than nonusers. Regression models revealed factors significantly associated with opioid use, including male sex, body mass index, allodynia, increasing monthly headache frequency, Total Pain Index score (excluding head, face, neck/shoulder), anxiety, depression, ≥1 cardiovascular com...Continue Reading

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Citations

Oct 24, 2020·Journal of Primary Care & Community Health·David W DodickHoward Weintraub
Apr 24, 2021·Journal of Neurointerventional Surgery·Joshua S CatapanoAshutosh P Jadhav
Jun 22, 2021·Plastic and Reconstructive Surgery. Global Open·Ricardo OrtizWilliam G Austen
Jul 17, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Mia T MinenRobert Duarte

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Clinical Trials Mentioned

NCT01648530

Software Mentioned

CaMEO

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