Characterizing the glycome of the mammalian immune system

Immunology and Cell Biology
Stuart M HaslamAnne Dell

Abstract

The outermost layer of all immune cells, the glycocalyx, is composed of a complex mixture of glycoproteins, glycolipids and lectins, which specifically recognize particular glycan epitopes. As the glycocalyx is the cell's primary interface with the external environment many biologically significant events can be attributed to glycan recognition. For this reason the rapidly expanding glycomics field is being increasingly recognized as an important component in our quest to better understand the functioning of the immune system. In this review, we highlight the current status of immune cell glycomics, with particular attention being paid to T- and B-lymphocytes and dendritic cells. We also describe the strategies and methodologies used to define immune cell glycomes.

References

Nov 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·A AruffoI Stamenkovic
Dec 1, 1992·Glycobiology·S Doubet, P Albersheim
Oct 13, 1989·Science·N Sharon, H Lis
Dec 1, 1989·Trends in Biochemical Sciences·S DoubetP Albersheim
Mar 1, 1970·The Journal of Experimental Medicine·C Collotti, S Leskowitz
Dec 14, 1995·Nature·N L PerilloL G Baum
May 12, 1995·The Journal of Biological Chemistry·R P McEverR D Cummings
Apr 5, 2000·The Journal of Biological Chemistry·M GalvanL G Baum
Apr 5, 2000·The Journal of Experimental Medicine·L E HarringtonR Ahmed
Jan 3, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·S Tsuboi, M Fukuda
May 8, 2002·The Journal of Experimental Medicine·Lei JinHenry H Wortis
Dec 3, 2002·The Journal of Biological Chemistry·Anne Marie MoodyEllis L Reinherz
Feb 4, 2003·Nature Reviews. Immunology·Robert I LechlerLaurence A Turka
Oct 2, 2003·Current Opinion in Cell Biology·Alessandra Cambi, Carl G Figdor
Oct 22, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Timothy K StarrKristin A Hogquist
Nov 25, 2003·European Journal of Immunology·Gonzalo G Garcia, Richard A Miller
Mar 30, 2004·Biochemical and Biophysical Research Communications·Bruce Y MaAtsuo Ochi
Jun 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Bhanu P Pappu, Protul A Shrikant
Jun 25, 2004·Nucleic Acids Research·Klaus Karl Lohmann, Claus-W von der Lieth
Dec 9, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Rodney MorganBaiyong Li
Dec 18, 2004·Journal of Immunological Methods·Hermann R BohnenkampThomas Noll

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Citations

Apr 7, 2010·Cellular and Molecular Life Sciences : CMLS·Martin Frank, Siegfried Schloissnig
Mar 9, 2011·Journal of Inherited Metabolic Disease·Luisa SturialeDomenico Garozzo
Mar 17, 2009·Journal of Proteome Research·Yunsen LiDapeng Zhou
Aug 24, 2010·Omics : a Journal of Integrative Biology·Garima GuptaSrinivasa-Gopalan Sampathkumar
May 31, 2011·Frontiers in Bioscience (Scholar Edition)·Dapeng ZhouKatja Michael
Nov 16, 2013·Nature Chemical Biology·Margreet A Wolfert, Geert-Jan Boons
Jan 10, 2012·Current Opinion in Chemical Biology·Daniel KolarichPeter H Seeberger
Jul 15, 2009·Immunological Reviews·Linda G Baum, Paul R Crocker
Nov 30, 2011·Journal of Mass Spectrometry : JMS·Luisa SturialeDomenico Garozzo
Jan 18, 2011·Proteomics·Martin Pabst, Friedrich Altmann
Sep 5, 2015·Analytical Cellular Pathology (Amsterdam)·Ewa PochećAnna Lityńska
Nov 6, 2013·FEMS Microbiology Reviews·Wander Van BreedamHans J Nauwynck
Apr 15, 2015·Clinical Hemorheology and Microcirculation·Ilya Reviakine
Mar 8, 2012·Epigenetics : Official Journal of the DNA Methylation Society·Vlatka ZoldošGordan Lauc
Apr 30, 2013·Biochimica Et Biophysica Acta·Matthew P CampbellNiclas G Karlsson
Mar 10, 2015·Chromatographia·Kathrin StavenhagenManfred Wuhrer
Nov 23, 2016·Immunology and Cell Biology·Christian BüllGosse J Adema
Jun 26, 2018·Chemistry : a European Journal·Riikka Arppe-TabbaraThomas Just Sørensen
Sep 17, 2009·Molecular BioSystems·Richard D Cummings
Mar 23, 2011·The Journal of Immunology : Official Journal of the American Association of Immunologists·Stephan SchlickeiserBirgit Sawitzki
Jul 26, 2014·Shock·Kubra KamisogluIoannis P Androulakis
Aug 19, 2018·Nature Communications·N GiovannoneC J Dimitroff
Dec 19, 2018·Frontiers in Immunology·Sarah J MeyerLars Nitschke
Feb 15, 2019·Frontiers in Immunology·Tao ZhangRobbert M Spaapen
Feb 10, 2010·Immunopharmacology and Immunotoxicology·Bernd Lepenies, Peter H Seeberger
Mar 27, 2020·Scientific Reports·Nan JiaRichard D Cummings
Jan 9, 2019·Frontiers in Immunology·Nicholas GiovannoneCharles J Dimitroff
Dec 9, 2020·Matrix Biology : Journal of the International Society for Matrix Biology·Payton L MarshallPaul L Bollyky
Feb 23, 2021·Frontiers in Cell and Developmental Biology·Franziska Krautter, Asif J Iqbal
Feb 11, 2010·Journal of Proteome Research·Natalia V ArtemenkoPauline M Rudd

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