CHARMM36m: an improved force field for folded and intrinsically disordered proteins

Nature Methods
Jing HuangAlexander D MacKerell


The all-atom additive CHARMM36 protein force field is widely used in molecular modeling and simulations. We present its refinement, CHARMM36m (, with improved accuracy in generating polypeptide backbone conformational ensembles for intrinsically disordered peptides and proteins.


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