Charting a map through the cellular reprogramming landscape

Cell Stem Cell
Lu Wen, Fuchou Tang

Abstract

Analysis of the molecular mechanisms underlying somatic cell reprogramming into iPSCs is hampered by low efficiency of conversion and resulting cellular heterogeneity. In this issue of Cell Stem Cell, Zunder et al. (2015) utilize mass cytometry to perform high-throughput, single-cell analyses and provide a detailed molecular roadmap of the reprogramming process.

References

Dec 29, 2013·Trends in Cell Biology·Aliaksandra Radzisheuskaya, José C R Silva
Apr 1, 2014·Cell·Alejandro Sánchez Alvarado, Shinya Yamanaka
May 13, 2014·Cell·Lu Wen, Fuchou Tang
Oct 2, 2014·Nature Cell Biology·Philipp S HoppeTimm Schroeder
Feb 7, 2015·Cell Stem Cell·Jun XuHongkui Deng

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Citations

Oct 16, 2015·Nature Reviews. Genetics·Omer Schwartzman, Amos Tanay
Apr 14, 2016·The New England Journal of Medicine·Sonja A RasmussenLyle R Petersen
Mar 31, 2016·The New England Journal of Medicine·Rita W DriggersOlli Vapalahti
Apr 7, 2016·The New England Journal of Medicine·Adriano N HazinUNKNOWN Microcephaly Epidemic Research Group

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