Charting plasticity in the regenerating maps of the mammalian olfactory bulb.

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
Diana M Cummings, Leonardo Belluscio

Abstract

The anatomical organization of a neural system can offer a glimpse into its functional logic. The basic premise is that by understanding how something is put together one can figure out how it works. Unfortunately, organization is not always represented purely at an anatomical level and is sometimes best revealed through molecular or functional studies. The mammalian olfactory system exhibits organizational features at all these levels including 1) anatomically distinct structural layers in the olfactory bulb, 2) molecular maps based upon odorant receptor expression, and 3) functional local circuits giving rise to odor columns that provide a contextual logic for an intrabulbar map. In addition, various forms of cellular plasticity have been shown to play an integral role in shaping the structural properties of most neural systems and must be considered when assessing each system's anatomical organization. Interestingly, the olfactory system invokes an added level of complexity for understanding organization in that it regenerates both at the peripheral and the central levels. Thus, olfaction offers a rare opportunity to study both the structural and the functional properties of a regenerating sensory system in direct response t...Continue Reading

References

Jun 15, 1979·The Journal of Comparative Neurology·W B StewartG M Shepherd
Jan 1, 1994·Brain Research. Brain Research Reviews·P C Brunjes
May 20, 1994·Science·C Lois, A Alvarez-Buylla
Feb 16, 1996·Science·C LoisA Alvarez-Buylla
Nov 15, 1996·Cell·P MombaertsR Axel
Feb 12, 1998·Neuron·L BelluscioR Axel
Nov 26, 1999·The Journal of Comparative Neurology·M S BaileyM T Shipley
Sep 20, 2002·Nature·Leonardo BelluscioLawrence C Katz
Nov 15, 2002·The European Journal of Neuroscience·Beate WinnerH Georg Kuhn
Nov 1, 1950·Electroencephalography and Clinical Neurophysiology·E D ADRIAN
Jun 5, 2004·Science·Dong-Jing ZouStuart Firestein
Jun 14, 2005·Nature Neuroscience·Michael A HackMagdalena Götz
Jun 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Masahiro Yamaguchi, Kensaku Mori
Mar 21, 2006·Nature Neuroscience·Mariel A Kerr, Leonardo Belluscio
Apr 25, 2006·FEBS Letters·Simone PifferiAnna Menini
Aug 10, 2006·Proceedings of the National Academy of Sciences of the United States of America·David C WillhiteWei R Chen
Sep 23, 2006·Science·Takeshi ImaiHitoshi Sakano
Oct 13, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mariana AlonsoPierre-Marie Lledo
Nov 3, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Carolyn A MarksLeonardo Belluscio
Nov 17, 2006·Nature·Jayaram ChandrashekarCharles S Zuker
Dec 13, 2006·Angewandte Chemie·Takeshi SerizawaTatsuki Kitayama
Jan 12, 2007·Proceedings of the National Academy of Sciences of the United States of America·Alexander T CheslerStuart Firestein
Feb 22, 2007·The Journal of Comparative Neurology·S Parrish-AungstA C Puche
May 8, 2007·The Journal of Comparative Neurology·Brett A Johnson, Michael Leon
May 12, 2007·Current Biology : CB·Luxiang CaoJoseph A Gogos
Jun 1, 2007·Development·Julien A Dal ColIvan Rodriguez
Jun 15, 2007·Developmental Neurobiology·Mary C Whitman, Charles A Greer
Jun 22, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Dong-Jing ZouStuart Firestein

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Citations

Oct 13, 2006·Annual Review of Cell and Developmental Biology·Peter Mombaerts
Jul 26, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ning ChengLeonardo Belluscio
Oct 1, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ning ChengLeonardo Belluscio
Jul 9, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Diana M Cummings, Leonardo Belluscio
Apr 4, 2014·Journal of Neurotrauma·Elizabeth SteuerLeonardo Belluscio
Dec 21, 2019·Brain Structure & Function·Andrea HunyadiÉva Rácz

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