Jun 7, 2006

Checkpoint activation: don't get mad too much

Current Biology : CB
Péter Lénárt, Jan-Michael Peters

Abstract

The Mad2 protein is required to delay sister chromatid separation until all chromosomes have been aligned on the mitotic spindle. Two recent studies provide new insights into how Mad2 contributes to this remarkable task.

Mentioned in this Paper

Cell Cycle Proteins
MAD2L1 protein, human
Mitotic Spindle Apparatus
Genes, cdc
MXI1 wt Allele
Repressor Molecules
Chromatids
Cell Cycle
MXI1 gene
Chromosomes

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