Chelicerate Hox genes and the homology of arthropod segments

Evolution & Development
A AbzhanovT C Kaufman

Abstract

Genes of the homeotic complex (HOM-C) in insects and vertebrates are required for the specification of segments along the antero-posterior axis. Multiple paralogues of the Hox genes in the horseshoe crab Limulus poliphemus have been used as evidence for HOM-C duplications in the Chelicerata. We addressed this possibility through a limited PCR survey to sample the homeoboxes of two spider species, Steatoda triangulosa and Achaearanea tepidariorum. The survey did not provide evidence for multiple Hox clusters although we have found apparent duplicate copies of proboscipedia (pb) and Deformed (Dfd). In addition, we have cloned larger cDNA fragments of pb, zerknullt (zen/Hox3) and Dfd. These fragments allowed the determination of mRNA distribution by in situ hybridization. Our results are similar to the previously published expression patterns of Hox genes from another spider and an oribatid mite. Previous studies compared spider/mite Hox gene expression patterns with those of insects and argued for a pattern of segmental homology based on the assumption that the co-linear anterior boundaries of the Hox domains can be used as markers. To test this assumption we performed a comparative analysis of the expression patterns for UBX/ABD...Continue Reading

References

Jan 24, 1992·Cell·W McGinnis, R Krumlauf
Dec 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M T MurthaF H Ruddle
Apr 15, 1991·American Journal of Ophthalmology·D M ArmestoJ D Goosey
Apr 30, 1981·Nature·G Morata, S Kerridge
Aug 1, 1995·Current Opinion in Genetics & Development·R Warren, S Carroll
Dec 1, 1994·Molecular Phylogenetics and Evolution·P Snow, L W Buss
Sep 1, 1993·Molecular Phylogenetics and Evolution·P CartwrightL W Buss
Aug 1, 1994·Current Biology : CB·G PanganibanS B Carroll
Sep 29, 1995·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·M Akam
Aug 6, 1996·Proceedings of the National Academy of Sciences of the United States of America·F FalcianiS Brown
Feb 13, 1997·Nature·M Averof, S M Cohen
Jan 1, 1997·International Review of Cytology·B T Rogers, T C Kaufman
Jun 1, 1997·Molecular Phylogenetics and Evolution·S Q IrvineM Q Martindale
Jun 1, 1997·Current Biology : CB·E L Jockusch, L M Nagy
May 16, 1998·Nature·J L BooreW M Brown
Sep 2, 1998·Proceedings of the National Academy of Sciences of the United States of America·W G DamenD Tautz
Sep 2, 1998·Proceedings of the National Academy of Sciences of the United States of America·M J Telford, R H Thomas
Nov 13, 1998·Development Genes and Evolution·W G Damen, D Tautz
Nov 13, 1998·Development Genes and Evolution·M J Telford, R H Thomas
Sep 1, 1999·Proceedings of the National Academy of Sciences of the United States of America·A Abzhanov, T C Kaufman
Apr 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·M Akam
Jul 1, 1993·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·R W BeemanR E Denell
Feb 1, 1964·Comparative Biochemistry and Physiology·J AWAPARA, J W CAMPBELL
Sep 23, 2008·Evolution & Development·Chris Todd Hittinger, Sean B Carroll

❮ Previous
Next ❯

Citations

Oct 19, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Wim G M Damen
Sep 15, 2004·Development Genes and Evolution·Franck SimonnetEric Quéinnec
Jul 4, 2006·Development Genes and Evolution·Ralf Janssen, Wim G M Damen
Jul 6, 2006·Development Genes and Evolution·Michaël ManuelHervé Le Guyader
Feb 21, 2007·Development Genes and Evolution·Daniel Papillon, Maximilian J Telford
Jul 9, 2002·Current Opinion in Genetics & Development·Michalis Averof
Apr 4, 2003·Current Opinion in Genetics & Development·Cheryl C Hsia, William McGinnis
Dec 20, 2007·Arthropod Structure & Development·Angelika StollewerkMathias Weller
Mar 27, 2001·Nature Reviews. Genetics·R A Raff
Mar 17, 2012·Proceedings of the National Academy of Sciences of the United States of America·Sara KhadjehNikola-Michael Prpic
Mar 16, 2007·Frontiers in Zoology·Evelyn E SchwagerWim G M Damen
Aug 24, 2011·Frontiers in Zoology·Leandro DragoAlessandro Minelli
Nov 2, 2012·EvoDevo·Joshua F Coulcher, Maximilian J Telford
Sep 13, 2007·PloS One·Najmus MahfoozAleksandar Popadić
Mar 7, 2014·Frontiers in Zoology·Ralf JanssenGraham E Budd
Apr 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·M Akam
Jan 16, 2013·Annual Review of Entomology·Alison Heffer, Leslie Pick
Mar 17, 2001·Evolution & Development·T D ShippyR E Denell
Jan 25, 2002·Evolution & Development·A Popadić, L Nagy
May 15, 2002·Evolution & Development·Emmanuele Mouchel-VielhJean S Deutsch
May 15, 2002·Evolution & Development·Christopher J LoweGregory A Wray
Dec 21, 2002·Evolution & Development·Cynthia L Hughes, Thomas C Kaufman
Dec 24, 2003·Médecine sciences : M/S·François Bonneton
Aug 11, 2010·Arthropod Structure & Development·Matthias PechmannNikola-Michael Prpic
Aug 28, 2004·Evolution & Development·Steffen Harzsch
Jun 12, 2004·Biological Reviews of the Cambridge Philosophical Society·Geoff A Boxshall
Jul 25, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·David C BlackburnNadean L Brown
Nov 16, 2005·Annual Review of Genetics·David R Angelini, Thomas C Kaufman
Nov 10, 2000·Developmental Biology·A Abzhanov, T C Kaufman
Apr 26, 2015·Insect Biochemistry and Molecular Biology·Zhiyong DiZhijian Cao
Feb 8, 2006·Developmental Biology·Kristen A PanfilioThomas C Kaufman
May 12, 2016·EvoDevo·Ryan M PaceLisa M Nagy
Jul 1, 2016·Current Opinion in Genetics & Development·Daniel J Leite, Alistair P McGregor
Aug 2, 2001·The Journal of Experimental Zoology·T H Waterman
Aug 2, 2017·BMC Biology·Evelyn E SchwagerAlistair P McGregor
Apr 30, 2003·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Gregory K Davis, Nipam H Patel
Apr 12, 2008·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Alistair P McGregorWim G M Damen
Sep 12, 2008·Zoological Journal of the Linnean Society·Bradley C Livezey, Richard L Zusi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Evolution & Development
Cynthia L Hughes, T C Kaufman
Proceedings of the National Academy of Sciences of the United States of America
Wim G M DamenD Tautz
Proceedings of the National Academy of Sciences of the United States of America
M J Telford, R H Thomas
© 2021 Meta ULC. All rights reserved