PMID: 26328453Sep 4, 2015Paper

Chemical Characterization and Antimicrobial Activity Evaluation of Natural Oil Nanostructured Emulsions

Journal of Nanoscience and Nanotechnology
Everton N AlencarE Sócrates T Egitol

Abstract

The aim of this work was to investigate the antimicrobial activity of nanostructured emulsions based on copaiba (Copaifera langsdorffii) resin-oil, copaiba essential oil, and bullfrog (Rana catesbeiana Shaw) oil against fungi and bacteria related to skin diseases. Firstly, the essential oil was extracted from copaiba resin-oil and these oils, along with bullfrog oil, were characterized by gas chromatography combined with mass spectrometry (GC-MS). Secondly, nanostructured emulsion systems were produced and characterized. The antimicrobial susceptibility assay was performed, followed by the Minimum Inhibitory Concentration (MIC) determination, the bioautography assay, and the antibiofilm determination. Strains of the genera Staphylococcus, Pseudomonas, and Candida were used. The CG-MS analysis was able to identify the components of copaiba resin-oil, copaiba essential oil, and bullfrog oil. The MIC assay in association with the bioautography revealed that some esters of palmitic and oleic acids, a-curcumene, a-himachalene, isothujol, and α-fenchene--probably inhibited some strains. The nanostructured emulsions based on copaiba resin-oil and essential oil improved the antimicrobial activity of the pure oils, especially against St...Continue Reading

Citations

Mar 6, 2016·International Journal of Pharmaceutics·Andreza Rochelle do Vale MoraisAbdelhamid Elaissari
May 6, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lucas Amaral-MachadoEryvaldo S T Egito
Apr 11, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Renata RutckeviskiEryvaldo S T Egito
Oct 5, 2017·Journal of Chromatographic Science·Francisco Humberto Xavier-JuniorChristine Vauthier
Jan 17, 2020·Journal of Oleo Science·Leonardo M Q BarbosaEryvaldo S T Egito
Dec 14, 2019·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Lívia do Carmo SilvaMaristela Pereira
Jul 18, 2020·Drug Delivery and Translational Research·Ana Paula Dos Santos MatosEduardo Ricci-Júnior
Dec 18, 2020·Anais Da Academia Brasileira De Ciências·DivÂnia F F DE OliveiraAna LÚcia F Porto
Jul 2, 2019·Acta Pharmaceutica : a Quarterly Journal of Croatian Pharmaceutical Society and Slovenian Pharmaceutical Society, Dealing with All Branches of Pharmacy and Allied Sciences·Renata RutckeviskiEryvaldo Socrates Tabosa Do Egito

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