PMID: 737170Dec 19, 1978Paper

Chemical characterization of glomerular and tubular basement membranes of cattle of different ages

Biochimica Et Biophysica Acta
J P LangeveldU J van Haelst

Abstract

Glomerular and tubular basement membranes were isolated from fetal, neonatal, young and adult bovine kidneys. An isolation method with sieves for both glomeruli and tubules from the same kidney was developed. A detergent procedure appeared to give purer glomerular and tubular basement membrane preparations than the generally used sonication method. No large differences were found in the composition of glomerular and tubular basement membrane of adult animals. Glomerular and tubular basement membrane preparations of the four age groups showed an increase with age of hydroxylysine and both 3- and 4-hydroxyproline. The most marked increases appeared at different stages of development, that of tubular basement membrane being between fetal and neonatal stages and glomerular basement membrane between 18 weeks old and adult animals. The ratio of 3- to 4-hydroxyproline increased considerably during development. Total imino acid content was higher for both types of basement membrane from adult than from young animals, while total content of hydroxylysine plus lysine remained fairly constant. The increase in hydroxylation of lysine was accompanied by a corresponding change in glucose and galactose content so that the ratio of galactose t...Continue Reading

References

Aug 1, 1977·Biochimica Et Biophysica Acta·F S Ligler, G B Robinson
Dec 1, 1977·Canadian Journal of Biochemistry·N KalantE Tel
Oct 1, 1977·Kidney International·I KriskoC S Sato
Jan 1, 1977·Experimental Gerontology·H NiedermüllerA Kment
Jan 30, 1978·Archives of Biochemistry and Biophysics·J R Hoyer, R G Spiro
Apr 1, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·H AnttinenK I Kivirikko
Apr 1, 1975·The Tohoku Journal of Experimental Medicine·T SatoZ Yosizawa
Jan 1, 1976·Experimental Gerontology·N A McNelly, J E Dittmer
Sep 15, 1970·Biochemistry·N G Westberg, A F Michael
Aug 1, 1974·Hoppe-Seyler's Zeitschrift für physiologische Chemie·W FerwerdaW van Dijk
Oct 27, 1973·British Medical Journal·J M Darmady
Aug 1, 1974·Experimental and Molecular Pathology·S Lui, N Kalant
Feb 1, 1974·The Journal of Clinical Investigation·N A Kefalides

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Citations

Jan 1, 1982·The International Journal of Biochemistry·S A Taylor, R G Price
Jan 1, 1984·The International Journal of Biochemistry·J P LangeveldL H Monnens
Jan 1, 1985·The International Journal of Biochemistry·J P LangeveldJ H Veerkamp
Nov 1, 1981·Bioscience Reports·M E GrantR W Orkin
Aug 1, 1983·Bioscience Reports·M Rand-Weaver, R G Price
Sep 9, 1982·Biochimica Et Biophysica Acta·W H PetersS L Bonting

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