Abstract
Helichrysum faradifani (Asteraceae) is a perennial shrub growing in rocky and sandy places of Madagascar. The plant is used in the Malagasy traditional medicine as a wound-healing agent, disinfectant and for the treatment of syphilis, diarrhea, cough and headache. In the present work, we analysed the chemical composition of the essential oil distilled from the aerial parts of H. faradifani by GC-MS and evaluated its insecticidal activity against 2nd, 3rd and 4th instar larvae of the lymphatic filariasis vector Culex quinquefasciatus by acute toxicity assays. The most sensitive were 2nd instar (LC50 = 85.7 μL L-1) larvae. For the 3rd and 4th instar larvae, the estimated LC50 were 156.8 and 134.1 μL L-1, respectively. Monoterpene hydrocarbons (51.6%) were the major fraction of the essential oil, with the bicyclic α-fenchene (35.6%) as the predominant component. Sesquiterpene hydrocarbons (34.0%) were the second major group characterising the oil, with γ-curcumene (17.7%) as the most abundant component.
References
Jul 1, 1988·Journal of Ethnopharmacology·P Beaujard
Apr 29, 2009·Journal of Ethnopharmacology·P BremnerM Heinrich
Sep 10, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Emilia ManciniVincenzo De Feo
Mar 2, 2012·Natural Product Research·Marcello NicolettiPhilippe Rasoanaivo
May 3, 2012·Journal of Vector Ecology : Journal of the Society for Vector Ecology·K Mitchell-FosterC Lowenberger
Dec 11, 2014·Journal of Oleo Science·Luigi OrnanoArmandodoriano Bianco
Jun 22, 2015·Parasitology Research·Giovanni Benelli
Jul 8, 2015·Parasitology Research·Roman Pavela
Aug 5, 2015·Parasitology Research·Giovanni Benelli
Sep 12, 2015·Natural Product Research·Rianasoambolanoro RakotosaonaFilippo Maggi
Nov 7, 2015·Parasitology Research·Giovanni Benelli
Mar 5, 2016·Parasitology Research·Giovanni Benelli, Heinz Mehlhorn
Mar 31, 2016·Parasitology Research·Marimuthu Govindarajan, Giovanni Benelli
Jun 5, 2016·Experimental Parasitology·Roman Pavela, Giovanni Benelli
Aug 10, 2016·Phytochemistry·Claudia GiulianiMarta Mariotti Lippi
Oct 6, 2016·Insects·Giovanni BenelliThomas Walker
Oct 30, 2016·Trends in Plant Science·Roman Pavela, Giovanni Benelli
Nov 22, 2016·Enzyme and Microbial Technology·Giovanni Benelli
Jan 23, 2017·Parasitology International·Giovanni BenelliFilippo Maggi
Jan 28, 2017·Acta Tropica·Chithravel VadivalaganGiovanni Benelli
Jul 8, 2017·Acta Tropica·Giovanni Benelli, John C Beier
Nov 3, 2017·Acta Tropica·Giovanni Benelli
Citations
Feb 23, 2020·Plants·Delphin J R RabehajaMathieu Paoli
Jul 10, 2020·Natural Product Research·Basma NajarLuisa Pistelli
Jun 4, 2020·Insects·Jocelyne TampeMónica Rubilar