Chemical composition and tyrosinase inhibitory activity of Cinnamomum cassia essential oil

Botanical Studies
Chen-Tien ChangSu-Tze Chou

Abstract

Essential oils extracted from aromatic plants exhibit important biological activities and have become increasingly important for scientific research. The essential oil extracted from Cinnamomum cassia Presl (CC-EO) has various functional properties, however, little information is available regarding the tyrosinase inhibitory activity. Therefore, the objectives of this study were to investigate the chemical composition and tyrosinase inhibitory activity of the CC-EO. cis-2-methoxycinnamic acid (43.06%) and cinnamaldehyde (42.37%) were found to be the two major components of the CC-EO identified by gas chromatography-mass spectrometry (GC-MS). The inhibitory activities of CC-EO and its major constituents were further evaluated against mushroom tyrosinase. The results showed that CC-EO and cinnamaldehyde exhibited anti-tyrosinase activities with IC50 values of 6.16 ± 0.04 mg/mL and 4.04 ± 0.08 mg/mL, respectively. However, cis-2-methoxycinnamic acid did not show any anti-tyrosinase activity. The inhibition kinetics were analyzed by Lineweaver-Burk plots and second replots, which revealed that CC-EO and cinnamaldehyde were mixed-type inhibitors. The inhibition constants (Ki) for CC-EO and cinnamaldehyde were calculated to be 4.71 ±...Continue Reading

References

Feb 22, 1995·Biochimica Et Biophysica Acta·A Sánchez-FerrerF García-Carmona
Dec 16, 1998·International Journal of Immunopharmacology·W S KohM Y Han
Dec 20, 1999·Journal of Agricultural and Food Chemistry·I Kubo, I Kinst-Hori
Feb 7, 2001·Journal of Agricultural and Food Chemistry·H S Lee, Y J Ahn
Mar 7, 2002·Journal of Agricultural and Food Chemistry·Hoi-Seon Lee
Jun 27, 2002·Journal of Agricultural and Food Chemistry·Qing-Xi Chen, Isao Kubo
Dec 12, 2002·Journal of Agricultural and Food Chemistry·Hoi-Seon LeeMoo-Key Kim
May 2, 2003·Journal of Agricultural and Food Chemistry·Sung-Yum SeoNiti Sharma
Jun 4, 2005·Phytotherapy Research : PTR·Eugen J VerspohlEckhard Neddermann
Mar 16, 2006·Journal of Agricultural and Food Chemistry·Ritaro MatsuuraMasayoshi Sawamura
May 20, 2006·The American Journal of Chinese Medicine·Linda S M OoiVincent E C Ooi
Oct 31, 2007·Journal of Agricultural and Food Chemistry·Bruno MarongiuAntonio Rescigno
Dec 11, 2007·Canadian Journal of Physiology and Pharmacology·Jean-Jacques DugouaGideon Koren
Jun 27, 2009·Journal of Natural Products·Tran Minh NgocKiHwan Bae
May 13, 2011·Bioorganic & Medicinal Chemistry·María Eugenia ChiariMaría Cecilia Carpinella

❮ Previous
Next ❯

Citations

Jun 28, 2018·Clinical Pharmacology and Therapeutics·Hellen A Oketch-RabahJosef A Brinckmann
Apr 17, 2015·Pharmaceutical Biology·Wan Mohd Nuzul Hakimi Wan SallehRazauden Mohamed Zulkifli
Dec 3, 2016·Phytochemical Analysis : PCA·Paula GarcíaRicardo L E Furlan
Sep 29, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Chunling ZhangLingying Yu

❮ Previous
Next ❯

Software Mentioned

solution
SPSS
GCMS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Agricultural and Food Chemistry
Ritaro MatsuuraMasayoshi Sawamura
Bioscience, Biotechnology, and Biochemistry
Te-Sheng ChangHang-Ching Lin
© 2022 Meta ULC. All rights reserved