Abstract
As a classical herb pair in clinics of traditional Chinese medicine, Curcumae Rhizoma-Sparganii Rhizoma (HP CR-SR) is used for activating blood circulation to remove blood stasis. The essential components in HP CR-SR and its single herbs were comparatively analyzed using gas chromatography-mass spectrometry data. 66, 22, and 54 components in volatile oils of Curcumae Rhizoma, Sparganii Rhizoma, and HP CR-SR were identified, and total contents accounted for 75.416%, 91.857%, and 79.553% respectively. The thirty-eight components were found in HP CR-SR, and not detected in single herbs Curcumae Rhizoma and Sparganii Rhizoma. The highest radical trapping action was seen by an essential oil of HP CR-SR (IC50 = 0.59 ± 0.04 mg/mL). Furthermore, the HP CR-SR essential oil showed more remarkable cytotoxicity on tumor cell lines than that of the single herbs Curcumae Rhizoma and Sparganii Rhizoma in a dose-dependent manner: IC50 values showing 32.32 ± 5.31 μg/mL (HeLa), 34.76 ± 1.82 μg/mL (BGC823), 74.84 ± 1.66 μg/mL (MCF-7), 66.12 ± 11.23 μg/mL (SKOV3), and 708.24 ± 943.91 μg/mL (A549), respectively. In summary, the essential oil of HP CR-SR is different from any one of Curcumae Rhizoma and Sparganii Rhizoma, nor simply their superposit...Continue Reading
References
Sep 16, 1999·Archives of Biochemistry and Biophysics·P MerckeP E Brodelius
Oct 13, 2001·The Journal of Organic Chemistry·A Srikrishna, K Anebouselvy
Aug 1, 1963·Journal of Chromatography·H VANDENDOOL, P D KRATZ
Mar 17, 2006·Acta Pharmacologica Sinica·Xiao-Ru LiFang-Qiu Guo
Sep 19, 2006·The International Journal of Biochemistry & Cell Biology·Marian ValkoJoshua Telser
Dec 5, 2006·Cardiovascular Research·Barry Halliwell
Feb 3, 2007·Journal of Ethnopharmacology·Choong Yong UngYu Zong Chen
Jul 7, 2007·Journal of Chromatography. a·M Jalali Heravi, H Sereshti
Jan 22, 2009·Journal of Separation Science·Xiao-Ru LiChun-Di Hu
Sep 8, 2009·International Journal of Pharmaceutics·Yi ZhaoYing Zheng
Feb 18, 2011·Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·Jinglei Xiao, Dacheng Jiang
Sep 17, 2011·Journal of Ethnopharmacology·Ji-Yan SuZi-Ren Su
Oct 20, 2011·Natural Product Research·Ramanathan Sambath KumarNallasamy Venkateswara Murthy
Nov 30, 2011·Journal of Ethnopharmacology·Li LiuXuqin Shi
Aug 9, 2012·Journal of Ethnopharmacology·Shengpeng WangYitao Wang
Oct 2, 2012·Journal of Separation Science·Jiangang FuYizeng Liang
Nov 3, 2012·European Journal of Pharmacology·Yunyi LiuGuangyuan He
Aug 6, 2013·Journal of Ethnopharmacology·Amel BouzabataFélix Tomi
Oct 8, 2013·Antiviral Research·Qingjiao LiaoXulin Chen
Jun 15, 2011·Food Chemistry·Jian-Qing YuGuo-Lin Zou
Dec 23, 2014·Acta Pharmaceutica : a Quarterly Journal of Croatian Pharmaceutical Society and Slovenian Pharmaceutical Society, Dealing with All Branches of Pharmacy and Allied Sciences·Delair Silveira Dos SantosValdir Cechinel Filho
Mar 15, 2015·Journal of Pharmaceutical and Biomedical Analysis·Shuai SongJiabo Luo
Apr 11, 2015·Free Radical Biology & Medicine·Lingrong WenBao Yang
Apr 18, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Guolong LiHongbo Liu
Jun 16, 2015·Chinese Journal of Natural Medicines·Lin-Yan WangJin-Ao Duan
Sep 28, 2009·Analytical Methods : Advancing Methods and Applications·Lian-Fang YuYi-Zeng Liang
Citations
Sep 21, 2019·Journal of Enzyme Inhibition and Medicinal Chemistry·Yang Liu, Gangliang Huang
Jan 30, 2019·Scientific Reports·Almudena Pérez-SánchezVicente Micol
Aug 11, 2017·Chemistry & Biodiversity·Lanyue ZhangZhiyun Du
Jul 13, 2017·Current Microbiology·Piyamas AtiphasawornPatcharee Pripdeevech
Sep 7, 2018·Frontiers in Pharmacology·Xiaopei LiuChunhua Xia
Apr 15, 2020·Nutrition and Cancer·Sheema HashemAjaz A Bhat
Mar 12, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Liangjun YangHuafeng Pan
Mar 27, 2020·Frontiers in Pharmacology·Weilin ZhengLixing Cao
May 30, 2019·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·Cheng Hao YuWei Jun Ding
Nov 13, 2020·Journal of Ethnopharmacology·Jia JiaGaimei She
Jun 15, 2021·Frontiers in Public Health·Li ZhangChenghao Yu
Jul 10, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Shuying DaiQijin Shu
Jul 23, 2021·Journal of Ethnopharmacology·Xiao-Yun LiuGai-Mei She
Aug 2, 2021·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Runhua LiuYikun Sun
Jan 24, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Yukun YinLixiang Ding