Chemical composition of endemic Centaurea austro-anatolica and studies of its antimicrobial activity against multi-resistant bacteria

Acta Pharmaceutica : a Quarterly Journal of Croatian Pharmaceutical Society and Slovenian Pharmaceutical Society, Dealing with All Branches of Pharmacy and Allied Sciences
Aysel UgurMehmet Emin Duru

Abstract

Hexane, chloroform, ethyl acetate and ethanolic extracts of the aerial parts of Centaurea austro-anatolica Hub.-Mor. (Asteraceae) were evaluated against microorganisms, including multiresistant bacteria, using a paper disc diffusion method. The chloroform extract exhibited significant antibacterial activity toward all bacteria tested. The chemical composition of the chloroform extract was determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The major compounds of the extract were caryophyllene oxide (21.32 %), spathulenol (10.86 %), n-tricosanol (9.58 %) and geranyl isovalerate (8.71 %).

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Citations

Mar 14, 2020·BMC Complementary Medicine and Therapies·Huda NaeimAmira M Embaby
Aug 2, 2017·Asian Pacific Journal of Tropical Medicine·Sevil AlbayrakAhmet Aksoy
Jan 4, 2019·Cytotechnology·Fatih Çağlar ÇelikezenHasan Türkez

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