Abstract
The chemical investigation on endophytic fungus Annulohypoxylon cf. stygium in leaves of Anoectochilus roxburghii (Wall.) Lindl. has been performed. Sixteen compounds were isolated and their structures were identified as (-)-notoamide A, (-)-notoamide B, (+)-versicolamide B, notoamide C, notoamide D, stephacidin A, sterigmatocystin, dihydrosterigmatocystin, secosterigmatocystin, versiconol, averufanin, kipukasin D, kipukasin E, diorcinal, palmarumycin CP2 and (-)-(3R)-mellein methyl ether, respectively, by spectroscopic analysis and comparison with literature data. All the compounds were isolated from Annulohypoxylon genus for the first time. Sterigmatocystin and palmarumycin CP2 showed selective cytotoxic activities against HepG2, HeLa, MCF-7 and HT-29.
References
Feb 1, 1988·Chemical & Pharmaceutical Bulletin·M YamazakiY Horie
May 4, 2002·Planta medica·C H LiuR X Tan
Jul 5, 2003·Chemical & Pharmaceutical Bulletin·Yukiko TakenakaNobuo Hamada
Jun 26, 2004·Journal of Natural Products·Christine KlemkeGabriele M König
Feb 3, 2007·Chemical & Pharmaceutical Bulletin·Taridaporn BunyapaiboonsriKanokarn Kocharin
Feb 17, 2007·Angewandte Chemie·Hikaru KatoSachiko Tsukamoto
Mar 17, 2007·Bioorganic & Medicinal Chemistry·Shinji KamisukiYoshiyuki Mizushina
Jul 5, 2007·Journal of Natural Products·Ping JiaoDonald T Wicklow
Nov 6, 2007·Chemical & Pharmaceutical Bulletin·Wipapan PongcharoenKanlayanee Sriklung
Feb 1, 2008·Phytochemistry·Martha L Macías-RubalcavaAna Luisa Anaya
Apr 5, 2008·Angewandte Chemie·Thomas J GreshockRobert M Williams
Aug 30, 2008·Journal of Natural Products·Yousong DingRobert M Williams
Sep 2, 2008·Chemical & Pharmaceutical Bulletin·Hui-Ying HanXin-Sheng Yao
Nov 15, 2008·Journal of Natural Products·Sergio Martínez-LuisLuis Cubilla-Rios
Apr 27, 2010·Journal of Natural Products·Zhenyu LuWeiming Zhu
Mar 7, 2013·Archives of Pharmacal Research·Xianglan KongDehai Li
Mar 13, 2014·Letters in Applied Microbiology·C AlmeidaL Cubilla-Rios
Mar 29, 2014·Natural Product Research·Min ChenChang-Yun Wang
Jun 10, 2014·Journal of Natural Products·Anton N YurchenkoShamil Sh Afiyatullov
Jun 18, 2014·Chemistry & Biodiversity·Chun-Wei ChangIh-Sheng Chen
Jul 16, 2014·Marine Drugs·Wen-Jian LanLai-You Wang
Aug 27, 2014·The Journal of Organic Chemistry·Zeinab G KhalilRobert J Capon
Sep 11, 2014·Natural Products and Bioprospecting·Muna Ali Abdalla, Josphat C Matasyoh
Dec 17, 2014·Marine Drugs·Qifeng YaoShuhua Qi
May 15, 2015·The Journal of Antibiotics·Zhiran JuYonghong Liu
May 30, 2015·Journal of Asian Natural Products Research·Jie-Feng TianXin-Sheng Yao
Jun 11, 2015·Journal of Natural Products·Bin WangRobert H Cichewicz
Nov 6, 2015·Journal of Natural Products·Ya-Ming XuA A Leslie Gunatilaka
Nov 27, 2016·Archives of Pharmacal Research·Wei LiSang Hee Shim
Dec 24, 2016·Journal of Natural Products·Wei LiSang Hee Shim
Feb 22, 2017·Phytochemistry·Eric KuhnertMarc Stadler
Mar 10, 2017·Bioorganic & Medicinal Chemistry·Ittipon SiridechakornKhanitha Pudhom
Apr 11, 2017·Natural Product Research·Zhangshuang DengDachun Gong
Jun 24, 2017·Natural Product Research·Rebeca P MedinaSilvana M O Santin
Aug 2, 2017·Journal of Ethnopharmacology·Shenyi YeAilian Zhang
Aug 15, 2017·Phytochemistry·Praphatsorn SaetangChatchai Muanprasat
Nov 28, 2017·Journal of Photochemistry and Photobiology. B, Biology·Olívia Maria Campanini MacielHosana Maria Debonsi
Apr 7, 2018·Tetrahedron Letters·Kayo SugimotoSachiko Tsukamoto
Jan 10, 2019·Natural Product Research·Zhiyong XuJing Xu