Chemical Constituents of the Seed Cake of Camellia oleifera and Their Antioxidant and Antimelanogenic Activities

Chemistry & Biodiversity
Wan-Fang ZhuJie Zhang

Abstract

There is a growing interest in the exploitation of agricultural byproducts. This study explored the potential beneficial health effects from the main biowaste, tea seed pomace of Camellia oleifera Abel (Theaceae), produced when tea seed is processed. Eighteen compounds were isolated from the 70% EtOH extract of the seed cake of C. oleifera. Their structures were determined by ESI-MS, 1 H- and 13 C-NMR together with literature data. All fractions and compounds were evaluated for the antioxidant and melanogenesis inhibitory activities. As the result, AcOEt fraction has the best in vitro antioxidant and antimelanogenesis activities, compounds 7 - 12 and 15 showed remarkable antioxidant activity, compounds 4, 6, 8, and 15 - 17 exhibited superior inhibitory activities against melanogenesis. Furthermore, tyrosinase inhibitory activity assay suggested that compound 8 could suppress melanogenesis by inhibiting the expression of tyrosinase.

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May 11, 2017·Chemistry & Biodiversity·Cai-Ling SunJie Zhang

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Citations

Feb 29, 2020·Preparative Biochemistry & Biotechnology·Guiming FuYin Wan
May 17, 2019·International Journal of Molecular Sciences·Laura SistiFabrice Leroux
Dec 18, 2020·Mycology·Surasak PrachyaAcharavadee Pansanit
May 1, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ana Margarida Teixeira, Clara Sousa
Jul 3, 2021·International Journal of Molecular Sciences·Kyuri KimKyung-Min Lim

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