Chemical Differentiation of Genetically Identified Atractylodes japonica , A. macrocephala , and A. chinensis Rhizomes Using High-Performance Liquid Chromatography with Chemometric Analysis

Evidence-based Complementary and Alternative Medicine : ECAM
Jung-Hoon KimGuemsan Lee

Abstract

The rhizome of Atractylodes japonica, which is a herbal medicine used for gastrointestinal therapeutics, has been categorized with A. macrocephala rhizome or A. chinensis rhizome based on different therapeutic criteria in Korea, China, and Japan. In the present study, 61 A. japonica, A. macrocephala, and A. chinensis rhizomes were collected from Korea and China and were genetically identified by internal transcribed spacer sequencing analysis. Chromatographic profiles were obtained from high-performance liquid chromatography analysis of the methanol and hot-water extracts of Atractylodes rhizomes and chemical differentiation of the rhizomes was carried out using chemometric statistical analyses such as principal component analysis, hierarchical clustering analysis, and Pearson's correlation coefficient analysis. The results from chromatographic profiles and chemometric analyses demonstrate that A. japonica rhizomes showed apparent chemical differences from A. macrocephala and A. chinensis rhizomes in the methanol extracts. In contrast, no clear distinction was apparent for the hot-water extracts of Atractylodes rhizomes, especially A. chinensis rhizomes. These results indicate that there is a clear chemical difference between A...Continue Reading

References

Feb 14, 2002·Molecular Phylogenetics and Evolution·Núria Garcia-JacasRoser Vilatersana
Feb 8, 2006·Biological & Pharmaceutical Bulletin·Mao ShibaMasaki Aburada
Jun 30, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Uta CeglarekJoachim Thiery
Jul 17, 2010·Computer Methods in Biomechanics and Biomedical Engineering·Maureen StoneJerry L Prince
Jan 1, 2011·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Jue ZhouYongping Yu
Nov 26, 2013·Analytica Chimica Acta·Mohammad GoodarziYvan Vander Heyden

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Citations

Oct 11, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Eui-Jeong DohJung-Hoon Kim

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Datasets Mentioned

BETA
AB219409

Methods Mentioned

BETA
PCR
electrophoresis
PCA

Software Mentioned

ClustalW
Chemstation
R
DNADist

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