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Chemical integration of proteins in signaling and development

bioRxiv

Mar 1, 2015

Jeffrey M. Dick

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Abstract

In developing embryos of eukaryotes, varying concentrations and/or duration of exposure to morphogens induce and repress transcription factors (TFs) in a regular order, thereby acting as signals for cell differentiation. I present a chemical thermodynamic model for the formation and deg...read more

Mentioned in this Paper

Complex (molecular entity)
Chemicals
Ligands
Protein Biosynthesis
Cell Surface
Endocytosis
Vertebrates
SHH gene
Patterns
Signal Transduction
2
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  • Chemical integration of proteins in signaling and development

    bioRxiv

    Mar 1, 2015

    Jeffrey M. Dick

    PMID: 990015826

    DOI: 10.1101/015826

    Abstract

    In developing embryos of eukaryotes, varying concentrations and/or duration of exposure to morphogens induce and repress transcription factors (TFs) in a regular order, thereby acting as signals for cell differentiation. I present a chemical thermodynamic model for the formation and deg...read more

    Mentioned in this Paper

    Complex (molecular entity)
    Chemicals
    Ligands
    Protein Biosynthesis
    Cell Surface
    2

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