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Chemical modifications of phospholipases A2 from snake venoms: effects on catalytic and pharmacological properties

Toxicon : Official Journal of the International Society on Toxinology

Dec 15, 2003

Andreimar Martins Soares, José Roberto Giglio

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Abstract

Phospholipases A2 (PLA2s) constitute major components of snake venoms and have been extensively investigated not only because they are very abundant in these venoms but mainly because they display a wide range of biological effects, including neurotoxic, myotoxic, cytotoxic, edema-induc...read more

Mentioned in this Paper

Enzymes, antithrombotic
Naja melanoleuca
Amino Acid [EPC]
Enzymes, peripheral vasodilators
Naja
Muscle Cells
Crotalus adamanteus
Catalytic Domain
Inactivation
Parasites
Paper Details
References
    • References95
    • Citations69
    • References95
    • Citations69
  • Chemical modifications of phospholipases A2 from snake venoms: effects on catalytic and pharmacological properties

    Toxicon : Official Journal of the International Society on Toxinology

    Dec 15, 2003

    Andreimar Martins Soares, José Roberto Giglio

    PMID: 15019487

    DOI: 10.1016/j.toxicon.2003.11.004

    Abstract

    Phospholipases A2 (PLA2s) constitute major components of snake venoms and have been extensively investigated not only because they are very abundant in these venoms but mainly because they display a wide range of biological effects, including neurotoxic, myotoxic, cytotoxic, edema-induc...read more

    Mentioned in this Paper

    Enzymes, antithrombotic
    Naja melanoleuca
    Amino Acid [EPC]
    Enzymes, peripheral vasodilators
    Naja

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    References
    • References95
    • Citations69
    • References95
    • Citations69
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