Chemical Profile and Biological Activity of Cherimoya (Annona cherimola Mill.) and Atemoya (Annona atemoya) Leaves.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Giuseppe ManninoCinzia Margherita Bertea

Abstract

Annona cherimola (Cherimoya) and Annona atemoya (Atemoya) are tropical plants known for their edible fruit. Scientific data suggest that their leaves, used in traditional medicine in the form of teas or infusions without evidence of toxicity, contain several bioactive compounds. However, only Annona muricata among all the Annona species is currently used in the nutraceutical field, and its dried leaves are marketed for tea preparation. In this work, we explored the nutraceutical potential of Atemoya and Cherimoya leaves, by evaluating their chemical profile and functional properties. Phytochemical analyses showed large amounts of phenolic compounds, in particular proanthocyanidins, and identified 18 compounds, either flavonoids or alkaloids. Concerning biological activity, we found antioxidative properties correlated with polyphenols, and antiproliferative activity against HeLa and HepG2 cell lines correlated with alkaloids. The obtained results demonstrate the potential use of Annona cherimola leaves for the preparation of dietary supplements aimed to promote the physiological redox balance. Moreover, the varietal comparison suggests that two commercial cultivars (Campas and White) and the local Torre 1, better suit this purpo...Continue Reading

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Citations

Apr 4, 2021·International Journal of Molecular Sciences·Giuseppe ManninoCarla Gentile
May 1, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jesús Martínez-SolísMiguel Valdés
Jul 25, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Antonino LauriaAnnamaria Martorana
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gregoria GregoriouAndreas I Constantinou
Dec 10, 2020·Food Research International·Ana Sofía IsasCarina Van Nieuwenhove

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