PMID: 7544281Aug 1, 1995Paper

Chemical structures of the core region of Campylobacter jejuni O:3 lipopolysaccharide and an associated polysaccharide

European Journal of Biochemistry
G O AspinallA P Moran

Abstract

The complete structure for the core oligosaccharide region of the water-insoluble low-M(r) lipopolysaccharide of Campylobacter jejuni serotype O:3 from phenol/water extraction of bacterial cells was assigned through studies on derivatives of the liberated oligosaccharide. Structure determinations were performed using 1H-NMR and 31P-NMR spectroscopies, methylation analysis supported by fast-atom-bombardment mass spectrometry, and Smith degradation experiments. It was concluded that the complete chains in the core oligosaccharide had the following structure in which a proportion of the terminal residues were phosphorylated: [formula: see text] From a similar series of experiments, it was concluded that an associated polysaccharide, which was isolated from the water phase of the phenol/water extracts, had the following repeating unit in which a proportion of the previously unknown L-glycero-D-ido-heptose (L-alpha-D-ido-Hep) residues were present as 3-hydroxypropanoyl esters, and were not covalently linked to the lipopolysaccharide: [formula see: text]

References

Jan 1, 1991·Microbiology and Immunology·A al-HendyM Skurnik
Mar 1, 1988·Carbohydrate Research·D G PritchardN R Krishna
May 1, 1993·European Journal of Biochemistry·G O AspinallA P Moran

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Citations

Apr 6, 2005·FEMS Microbiology Reviews·Andrey V KarlyshevBrendan W Wren
Apr 18, 2002·Journal of the Neurological Sciences·Anthony P MoranEdward L Hogan
Dec 1, 1996·FEMS Immunology and Medical Microbiology·A P MoranB J Appelmelk
Mar 3, 2010·Proceedings of the National Academy of Sciences of the United States of America·Thomas W Cullen, M Stephen Trent
Jul 13, 2012·The Journal of Biological Chemistry·Matthew McCallumCarole Creuzenet
Dec 31, 2008·Infection and Immunity·Mario A MonteiroPatricia Guerry
Mar 18, 2011·Journal of Clinical Microbiology·Frédéric PolyPatricia Guerry
Feb 3, 2007·FEMS Immunology and Medical Microbiology·Adrian T Corcoran, Anthony P Moran
Dec 23, 2017·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Z IslamH P Endtz
Mar 24, 2006·FEMS Microbiology Letters·Adrian T CorcoranAnthony P Moran
Sep 19, 2006·FEMS Microbiology Letters·Michelle KilcoyneAngela V Savage
Jan 1, 1996·Critical Reviews in Microbiology·A PrestonM A Apicella
Apr 6, 2004·Organic & Biomolecular Chemistry·Søren M AndersenDavid R Bundle
Mar 15, 2015·Molecular Microbiology·Anthony WongCarole Creuzenet

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