Chemical Surface Modification of Polymeric Biomaterials for Biomedical Applications

Macromolecular Rapid Communications
Wei SunHong Chen

Abstract

This review focuses on the attachment of polymer brushes to polymeric biomaterial substrates by chemical surface modification methods for biomedical applications. In the first part of this paper, a general introduction to the synthesis of polymer brushes is given. Thereafter, a comprehensive overview of recent work on the chemical surface modification of polymeric biomaterials, with a focus on "grafting-to," "grafting-from," and "grafting-through" strategies, is provided. Finally, some representative cutting-edge biomedical applications of modified polymeric biomaterials, mainly including antifouling materials and biocompatible materials, are highlighted. On the basis of this literature study, a perspective on future trends in this field is provided.

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Citations

Jun 12, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Shuxiang ZhangHong Chen
Feb 27, 2021·Journal of Biomaterials Applications·Quan LiangHanyan Zou
Mar 16, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yanping CaoHong Chen
May 4, 2021·Biomacromolecules·Chiaki YoshikawaYoshinobu Tsujii
Jul 31, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Dayuan WangMingwu Shen

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