PMID: 6862592Jun 1, 1983

Chemiluminescence response of equine alveolar macrophages during stimulation with latex beads, or IgG-opsonized sheep red blood cells

R M Dyer, R W Leid


Isolated equine alveolar macrophages were shown to generate a luminol-dependent light response when challenged with a phagocytic stimulus. The chemiluminescent response was not detected with luminol prepared at 1.0 x 10(-5) or 1.0 x 10(-4) molar concentrations, but was readily quantitated when used at a 1.0 x 10(-3) molar concentration. Challenge of the alveolar macrophages with latex particles or with equine IgG-coated sheep red blood cells elicited the luminol-dependent light response, whereas unchallenged equine alveolar macrophages or those challenged with unopsonized erythrocytes failed to emit light above background levels. Latex-bead-challenged macrophages released 8.06 times the total amount of light as those equine alveolar macrophages challenged with equine IgG-opsonized erythrocytes. This study represents the first investigation on chemiluminescence and equine alveolar macrophages.


Feb 28, 1985·Journal of Immunological Methods·T UchidaS Hosaka
Aug 1, 1987·The Journal of Allergy and Clinical Immunology·M CluzelP Godard
Jan 1, 1989·Free Radical Biology & Medicine·V Vilim, J Wilhelm
Jul 1, 1992·Environmental Health Perspectives·E AnsoborloE Pujol
Dec 1, 1989·International Journal of Radiation Biology·P N LirsacH Metivier


Mar 23, 1978·The New England Journal of Medicine·B M Babior
Sep 1, 1975·The Journal of Clinical Investigation·R L BaehnerR B Johnston
Nov 1, 1975·The Journal of Clinical Investigation·I M GoldsteinG Weissmann
Dec 1, 1979·Infection and Immunity·J R HoidalJ E Repine
Jan 1, 1975·The Journal of Experimental Medicine·D B Drath, M L Karnovsky
Oct 1, 1976·The Journal of Clinical Investigation·B D ChesonB M Babior
Apr 1, 1975·The Journal of Infectious Diseases·L R DeChateletC E McCall
Mar 8, 1976·Biochemical and Biophysical Research Communications·R C Allen, L D Loose
Feb 1, 1971·The Journal of Clinical Investigation·M T VogtJ B Gee
Nov 1, 1971·Biochemical and Biophysical Research Communications·D RomeoF Rossi
Jun 1, 1970·The Journal of Clinical Investigation·J B GeeJ B Field
Jan 1, 1981·The Journal of Clinical Investigation·P D Lew, T P Stossel
May 1, 1958·Proceedings of the Society for Experimental Biology and Medicine·J H HANKS, J H WALLACE
Jun 1, 1963·The Journal of Cell Biology·R ORENM L KARNOVSKY

Related Concepts

Pulmonary Alveolar Structure
Red blood cells, blood product
Dall Sheep
Response to Light
Genus equus
Equus caballus
Sheep antigen

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