PMID: 8611325Jan 1, 1996Paper

Chemoembolization of head and neck cancer with carboplatine microcapsules

Acta Radiologica
N TomuraH Murota

Abstract

Fourteen patients with malignant tumor in the head and neck region were treated with infusion of carboplatine microcapsules (CBDCA-mc) via percutaneous super-selective catheterization. A microcatheter was advanced into a feeding artery using a coaxial catheter system. Eleven patients had over 30% reduction of the tumor size on CT within 1 month after embolization. Twelve patients had an increased amount of low attenuation tissue in the tumor on CT after embolization, suggesting increased necrosis in the tumor. No definite hematologic toxicity was found. A majority of patients complained of moderate pain in the embolized region immediately after embolization, easily relieved by i.v. analgesics. Chemoembolization using CBDCA-mc may be an effective therapeutic modality in advanced cases of head and neck cancer.

References

Sep 1, 1976·AJR. American Journal of Roentgenology·S WallaceR L Bree
Oct 1, 1988·Cardiovascular and Interventional Radiology·A H MatsumotoK H Barth
Mar 1, 1986·British Journal of Cancer·Y OkamotoY Amano
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Jul 1, 1984·International Journal of Radiation Oncology, Biology, Physics·H ShibuyaS Enomoto

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Citations

Sep 1, 2007·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·J PryorA De Crespigny

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