PMID: 11325259Apr 28, 2001Paper

Chemoenzymatic synthesis of neoglycopeptides: application to an alpha-Gal-terminated neoglycopeptide

The Journal of Organic Chemistry
D RamosW Klaffke

Abstract

A novel methodology for the enzymatic preparation from suitably derivatized oligosaccharides of N-linked neoglycopeptides using the microbial glutaminyl-peptide gamma-glutamyl transferase, transglutaminase (TGase), is described. N-Allyl glycosides of various oligosaccharides were photochemically coupled with cysteamine to yield amino-terminated thioether spacers, which were accepted by transglutaminase to transamidate the side-chain gamma-carboxamide group in the dipeptide Z-Gln-Gly.

Citations

Feb 14, 2002·Chemical Reviews·Benjamin G Davis
May 19, 2005·Chemical Communications : Chem Comm·Sébastien FortHugues Driguez
Mar 21, 2016·Journal of Biotechnology·Julia Pitzer, Kerstin Steiner
Oct 17, 2006·ChemMedChem·Yalong ZhangPeng George Wang
Dec 17, 2008·Angewandte Chemie·Christian P R Hackenberger, Dirk Schwarzer
Jul 28, 2011·Chemical Society Reviews·Alessandro Dondoni, Alberto Marra
Feb 27, 2004·Organic & Biomolecular Chemistry·Kannan P NaickerLai-Xi Wang
Oct 3, 2009·Chemistry : a European Journal·Alessandro DondoniAldo Roda
Jan 7, 2021·Chemical Society Reviews·Marzieh AhangarpourMargaret A Brimble
Dec 20, 2008·Chemical Reviews·David P GamblinBenjamin G Davis
Jun 6, 2009·The Journal of Organic Chemistry·Jasper DinkelaarGijsbert A van der Marel
Oct 15, 2009·Chemical Reviews·Shiro Kobayashi, Akira Makino
May 9, 2009·The Journal of Organic Chemistry·Michele FioreAlessandro Dondoni
Aug 25, 2018·Chemical Reviews·Chao Li, Lai-Xi Wang
Oct 28, 2004·Journal of the American Chemical Society·Masaaki SatoShin-Ichiro Nishimura

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